Structure of progesterone hydroquinone monohydrate (1:1:1), C21H30O2·C6H6O2·H2O

Zdzisław Gałdecki*, Paweł Grochulski, Zdzisław Wawrzak, William L. Duax

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The crystal structure of progesterone hydroquinone monohydrate was determined by means of X-ray diffraction methods:Mr=442.6, orthorhombic, P212121, a=14.680(2), b=22.725(3), c=7.334(1) Å, Va=2446.6(6) Å3, Z=4, Dx=1.190 M gm-3, Mo Kα radiation {Mathematical expression}, μ(Mo Kα)=0.75 cm-1, F(000)=948. The structure was solved using Multan;R=0.059, Rw=0.059 for 2736 reflections. This progesterone molecule has the most flattened A ring, relative to the rest of the skeleton, of all progesterone molecules studied so far. Steroid, hydroquinone, and water molecules form, by means of hydrogen bonds, two parallel chains connected with each other by hydrogen bonds.

Original languageEnglish (US)
Pages (from-to)983-991
Number of pages9
JournalJournal of Crystallographic and Spectroscopic Research
Volume19
Issue number6
DOIs
StatePublished - Dec 1 1989

ASJC Scopus subject areas

  • Structural Biology
  • Condensed Matter Physics
  • Spectroscopy

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