TY - JOUR
T1 - Structure/function studies of arsenite oxidoreductase and xanthine oxidase
AU - Manikandan, Palanichamy
AU - Ellis, Paul
AU - Kuhn, Peter
AU - Choi, Eun Young
AU - Hoffman, Brian
AU - Hille, Russ
PY - 2002
Y1 - 2002
N2 - The recently solved X-ray crystal structure of the molybdenum-containing arsenite oxidoreductase from Alcaligenes faecalis, is discussed, keeping in view the known mechanistic and spectroscopic information regarding the protein in a structural context. In addition, recent mechanistic studies of xanthine oxidase are covered, with the conclusion that the reaction mechanism is initiated by nucleophilic attack of a Mo-OH group on substrate.
AB - The recently solved X-ray crystal structure of the molybdenum-containing arsenite oxidoreductase from Alcaligenes faecalis, is discussed, keeping in view the known mechanistic and spectroscopic information regarding the protein in a structural context. In addition, recent mechanistic studies of xanthine oxidase are covered, with the conclusion that the reaction mechanism is initiated by nucleophilic attack of a Mo-OH group on substrate.
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M3 - Article
AN - SCOPUS:0036214674
SN - 0376-4710
VL - 41
SP - 22
EP - 31
JO - Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry
JF - Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry
IS - 1
ER -