Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: Asymmetric synthesis, neuroactivity, and structural characterization

Search results

• CCDC 900962: Experimental Crystal Structure Determination

  Juknaitě, L. (Contributor), Sugamata, Y. (Contributor), Tokiwa, K. (Contributor), Ishikawa, Y. (Contributor), Takamizawa, S. (Contributor), Eng, A. (Contributor), Sakai, R. (Contributor), Pickering, D. S. (Contributor), Frydenvang, K. (Contributor), Swanson, G. T. (Contributor), Kastrup, J. S. (Contributor) & Oikawa, M. (Contributor), Cambridge Crystallographic Data Centre, 2023

  DOI: 10.5517/ccdc.csd.ccz7j90, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.ccz7j90&sid=DataCite

  Dataset

• Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (2R)-IKM-159 at 2.3A resolution.

  Juknaitě, L. (Contributor), Sugamata, Y. (Contributor), Tokiwa, K. (Contributor), Ishikawa, Y. (Contributor), Takamizawa, S. (Contributor), Eng, A. (Contributor), Sakai, R. (Contributor), Pickering, D. S. (Contributor), Frydenvang, K. (Contributor), Swanson, G. T. (Contributor), Kastrup, J. S. (Contributor) & Oikawa, M. (Contributor), Protein Data Bank (PDB), Mar 20 2013

  DOI: 10.2210/pdb4ISU/pdb, https://www.wwpdb.org/pdb?id=pdb_00004isu

  Dataset