Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment

Masaki Handa, Karl A. Scheldt, Martin Bossart, Nan Zheng, William R. Roush*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

(Chemical Equation Presented) A synthesis of the C(1)-C(11) fragment of apoptolidin A has been accomplished by a convergent route involving the stereoselective glycosidation of 9 and the Suzuki cross-coupling reaction of bromodienoate 7 and the vinylborane generated via chemoselective hydroboration of diyne 6 with diisopinocampheylborane.

Original languageEnglish (US)
Pages (from-to)1031-1035
Number of pages5
JournalJournal of Organic Chemistry
Volume73
Issue number3
DOIs
StatePublished - Feb 1 2008

ASJC Scopus subject areas

  • Organic Chemistry

Fingerprint Dive into the research topics of 'Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment'. Together they form a unique fingerprint.

Cite this