La0.4Sr0.6Co0.8Fe0.2O3-δ (LSCF4682) perovskite was successfully synthesized by an assisted ammonium nitrate combustion method. The sample shows a sponge-like structure with meso and macropores distributed between interconnected nanosized crystallites (45 nm) with a specific surface area around 8 m2g-1. Cathode performance of LSCF4682 was investigated in the intermediate temperature range between 400 °C-700 °C by using symmetrical cell configuration on La0.8Sr0.2Ga0.8Mg0.2O3-δ (LSGM) electrolyte. The cathode polarization resistances Rc,p are 0.067 and 0.035 O.cm2 at 600 °C and 700 °C, respectively. The long-term behavior of Rc,p was studied by applying an accelerate aging at 800 °C and testing the polarization resistance at 700 °C as a function of time. After 500 h of aging, a degradation rate of 1/Rc,P dRc,P/dt = 0.002 h-1raises the Rc,p to 0.1 O.cm2 at 700 °C. A maximum power density of 1.23 Wcm-2 was achieved at 650 °C testing the LSCF cathode deposited on a porous SLT-LSGM supported multilayer cell. These results demonstrate that this material is a competitive SOFC cathode for the intermediate temperature operation.