Studying consciousness using direct recording from single neurons in the human brain

Moran Cerf*, Michael Mackay

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Consciousness represents a unity of experience derived from limitless possibilities and fierce competition for dominance within our brain. This unity reflects the compromise of an internal representation of the world that shapes our perception of the environment and guides the choices we make in interacting with it. Here we investigate the relationship between the external environment, our internal representation of it, and volition, using direct recording from single neurons in the brains of 12 patients with pharmacologically intractable epilepsy. In two novel experiments we pit the world within against the world outside, and separate the decision making processes within the brain from the sensation of volition. We show that subjects are capable of overriding external sensory input with internal imagery, and can directly control the firing rate of individual neurons in the medial temporal lobe. Additionally, we show that decision can be predicted before the conscious perception of volition, but that feeding this decision forward and bypassing volition leads to a gradual loss of predictive ability as the neurons alter their activity in response. We propose a working definition for consciousness based on these results, suggesting that consciousness involves our memory and experience of events and ties these together in a working narrative.

Original languageEnglish (US)
Title of host publicationCharacterizing Consciousness
Subtitle of host publicationFrom Cognition to the Clinic
EditorsStanislas Dehaene, Yves Christen
Pages133-146
Number of pages14
DOIs
StatePublished - Dec 1 2011

Publication series

NameResearch and Perspectives in Neurosciences
Volume18
ISSN (Print)0945-6082

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Studying consciousness using direct recording from single neurons in the human brain'. Together they form a unique fingerprint.

  • Cite this

    Cerf, M., & Mackay, M. (2011). Studying consciousness using direct recording from single neurons in the human brain. In S. Dehaene, & Y. Christen (Eds.), Characterizing Consciousness: From Cognition to the Clinic (pp. 133-146). (Research and Perspectives in Neurosciences; Vol. 18). https://doi.org/10.1007/978-3-642-18015-6_8