Subclinical orthostatic pulse pressure confirms mothers' ratings of ADHD in preschoolers

Vanessa Casavant*, Christina Chae, Afsheen Sherwani, Lawrence C. Perlmuter

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Subclinical levels of orthostatic hypotension (OH) have been linked to a variety of emotional and behavioral outcomes across the life span. These connections are not surprising, given the multitude of correlated conditions, including autonomic control, cardiovascular functioning, baroreceptor activity, and dopamine and serotonin. The current study assessed blood pressure regulation in healthy preschool children ages 3-5 (n=61). The Conner's Parent Rating Scale Revised was used to assess indexes of attention deficit hyperactivity disorder (ADHD). With the difference between standing and supine pulse pressure as the index of orthostatic blood pressure regulation, the results indicated that efficient pulse pressure regulation was significantly correlated with lower ADHD scores. Poorer orthostatic pulse pressure regulation in response to an orthostatic challenge may be a risk for symptoms of ADHD.

Original languageEnglish (US)
Pages (from-to)708-712
Number of pages5
Issue number5
StatePublished - May 2012


  • ADHD
  • Orthostatic hypotension
  • Pulse pressure

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Endocrine and Autonomic Systems
  • Neuropsychology and Physiological Psychology
  • Neurology
  • Biological Psychiatry
  • Cognitive Neuroscience
  • Developmental Neuroscience
  • Neuroscience(all)


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