Subdistal Appendages Stabilize the Ups and Downs of Ciliary Life

Domenico F. Galati*, Brian J. Mitchell, Chad G. Pearson

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

7 Scopus citations


Centrioles acquire subdistal appendages (sDAPs) during primary cilium formation. In this issue of Developmental Cell, Mazo et al. (2016) demonstrate that sDAPs keep cilia submerged within deep membrane invaginations. When sDAPs and centrosome cohesion are disrupted, cilia surface to the plasma membrane, which may alter mechanical and chemical signal transduction.

Original languageEnglish (US)
Pages (from-to)387-389
Number of pages3
JournalDevelopmental Cell
Issue number4
StatePublished - Nov 21 2016

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • Molecular Biology
  • Cell Biology
  • Developmental Biology


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