Subdistal Appendages Stabilize the Ups and Downs of Ciliary Life

Domenico F. Galati*, Brian J. Mitchell, Chad G. Pearson

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

6 Scopus citations

Abstract

Centrioles acquire subdistal appendages (sDAPs) during primary cilium formation. In this issue of Developmental Cell, Mazo et al. (2016) demonstrate that sDAPs keep cilia submerged within deep membrane invaginations. When sDAPs and centrosome cohesion are disrupted, cilia surface to the plasma membrane, which may alter mechanical and chemical signal transduction.

Original languageEnglish (US)
Pages (from-to)387-389
Number of pages3
JournalDevelopmental Cell
Volume39
Issue number4
DOIs
StatePublished - Nov 21 2016

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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