Subfornical organ: Duration of dipsogenic action of angiotensin-II

Joan Mitrius; Aryeh Routtenberg

doi:10.1016/0304-3940(77)90044-1

Subfornical organ: Duration of dipsogenic action of angiotensin-II

Joan Mitrius^*, Aryeh Routtenberg

^*Corresponding author for this work

Psychology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Prior evidence from our laboratory has implicated the subfornical organ (SFO) as a site of angiotensin-II (A-II)-induced drinking [22]. In the present study, animals were denied access to water for 0, 0.5 and 1.0 h following a single intracranial A-II injection into the SFO. Even after a delay of 1.0 h, A-II-injected animals showed increased water consumption compared to controls. Animals injected with A-II and tested immediately consumed significantly more water than the 1 h delay animals. Potential mechanisms involved in the maintenance of the drinking effect of A-II after 1 h and the decreased drinking in 1.0 h relative to the 0 h group were considered.

Original language	English (US)
Pages (from-to)	183-187
Number of pages	5
Journal	Neuroscience Letters
Volume	5
Issue number	3-4
DOIs	https://doi.org/10.1016/0304-3940(77)90044-1
State	Published - Jul 1977

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/0304-3940(77)90044-1

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title = "Subfornical organ: Duration of dipsogenic action of angiotensin-II",

abstract = "Prior evidence from our laboratory has implicated the subfornical organ (SFO) as a site of angiotensin-II (A-II)-induced drinking [22]. In the present study, animals were denied access to water for 0, 0.5 and 1.0 h following a single intracranial A-II injection into the SFO. Even after a delay of 1.0 h, A-II-injected animals showed increased water consumption compared to controls. Animals injected with A-II and tested immediately consumed significantly more water than the 1 h delay animals. Potential mechanisms involved in the maintenance of the drinking effect of A-II after 1 h and the decreased drinking in 1.0 h relative to the 0 h group were considered.",

author = "Joan Mitrius and Aryeh Routtenberg",

note = "Funding Information: Supported by NSF Grant NS HL 10768 ~o A,R. Gratitude is expressed to Shirley Snerling for her care~l technical &qsistance.",

year = "1977",

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doi = "10.1016/0304-3940(77)90044-1",

language = "English (US)",

volume = "5",

pages = "183--187",

journal = "Neuroscience Letters",

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TY - JOUR

T1 - Subfornical organ

T2 - Duration of dipsogenic action of angiotensin-II

AU - Mitrius, Joan

AU - Routtenberg, Aryeh

N1 - Funding Information: Supported by NSF Grant NS HL 10768 ~o A,R. Gratitude is expressed to Shirley Snerling for her care~l technical &qsistance.

PY - 1977/7

Y1 - 1977/7

N2 - Prior evidence from our laboratory has implicated the subfornical organ (SFO) as a site of angiotensin-II (A-II)-induced drinking [22]. In the present study, animals were denied access to water for 0, 0.5 and 1.0 h following a single intracranial A-II injection into the SFO. Even after a delay of 1.0 h, A-II-injected animals showed increased water consumption compared to controls. Animals injected with A-II and tested immediately consumed significantly more water than the 1 h delay animals. Potential mechanisms involved in the maintenance of the drinking effect of A-II after 1 h and the decreased drinking in 1.0 h relative to the 0 h group were considered.

AB - Prior evidence from our laboratory has implicated the subfornical organ (SFO) as a site of angiotensin-II (A-II)-induced drinking [22]. In the present study, animals were denied access to water for 0, 0.5 and 1.0 h following a single intracranial A-II injection into the SFO. Even after a delay of 1.0 h, A-II-injected animals showed increased water consumption compared to controls. Animals injected with A-II and tested immediately consumed significantly more water than the 1 h delay animals. Potential mechanisms involved in the maintenance of the drinking effect of A-II after 1 h and the decreased drinking in 1.0 h relative to the 0 h group were considered.

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JO - Neuroscience Letters

JF - Neuroscience Letters

IS - 3-4

ER -

Subfornical organ: Duration of dipsogenic action of angiotensin-II

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