Subfornical organ: Site of drinking elicitation by angiotensin II

John B. Simpson, Aryeh Routtenberg*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

287 Scopus citations

Abstract

Angiotensin II applied directly to the subfornical organ in a dose as small as 0.1 nanogram elicited short-latency drinking behavior in water-sated rats. Lesions in the body of this structure blocked drinking induced by angiotensin II applied to the basal telencephalon (including preoptic area). These results call attention to the subfornical organ as an important central nervous structure involved in the conrol of drinking behavior.

Original languageEnglish (US)
Pages (from-to)1172-1175
Number of pages4
JournalScience
Volume181
Issue number4105
DOIs
StatePublished - Jan 1 1973

ASJC Scopus subject areas

  • General

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