Substance abuse in schizophrenia: Biological factors mediating comorbidity and the potential role of atypical antipsychotic drugs

Myung A. Lee, Herbert Y Meltzer

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations

Abstract

Substance abuse is a common feature of many types of psychiatric disorders. The rate in schizophrenia is one of the highest for all psychiatric disorders (1). Comorbidity for substance abuse in schizophrenia has an important influence on course of illness, relapse, quality of life, morbidity, and compliance. High comorbidity for substance abuse may be related in part to biological factors. This chapter reviews the factors contributing to comorbidity for substance abuse in schizophrenia and the role of atypical antipsychotic drug in the treatment of substance abuse in patients with schizophrenia.

Original languageEnglish (US)
Title of host publicationSubstance Abuse in the Mentally and Physically Disabled
PublisherCRC Press
Pages77-102
Number of pages26
ISBN (Electronic)9780824744977
ISBN (Print)9780824705879
StatePublished - Jan 1 2001

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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    Lee, M. A., & Meltzer, H. Y. (2001). Substance abuse in schizophrenia: Biological factors mediating comorbidity and the potential role of atypical antipsychotic drugs. In Substance Abuse in the Mentally and Physically Disabled (pp. 77-102). CRC Press.