Substance Use Predicts Sustained Viral Suppression in a Community Cohort of Sexual and Gender Minority Youth Living with HIV

Casey D. Xavier Hall; Ethan Morgan; Camille Bundy; James E. Foran; Patrick Janulis; Michael E. Newcomb; Brian Mustanski

doi:10.1007/s10461-021-03179-y

Substance Use Predicts Sustained Viral Suppression in a Community Cohort of Sexual and Gender Minority Youth Living with HIV

Casey D. Xavier Hall, Ethan Morgan, Camille Bundy, James E. Foran, Patrick Janulis, Michael E. Newcomb, Brian Mustanski^*

^*Corresponding author for this work

Medical Social Sciences

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Retention in care and sustained viral suppression are integral outcomes in the care continuum for people living with HIV (PLWH) and HIV prevention; however, less is known about how substance use predicts sustained viral suppression over time. This study seeks to examine the predictive effects of substance use on sustained viral suppression in a sample of cisgender sexual minority men and gender minority PLWH (n = 163) drawn from a longitudinal sample in the Chicago area collected 2015–2019. Using data from 3 visits separated by 6 months, participants were coded persistently detectable, inconsistently virally suppressed, and consistently virally suppressed (< 40 copies/mL at all visits). Multinomial logistic regressions were utilized. About 40% of participants had sustained viral suppression. In multinomial logistic regressions, CUDIT-R predicted persistent detectable status and stimulant use was associated with inconsistent viral suppression. Substance use may create challenges in achieving sustained viral suppression, which has important implications for care and prevention.

Original language	English (US)
Pages (from-to)	3303-3315
Number of pages	13
Journal	AIDS and behavior
Volume	25
Issue number	10
DOIs	https://doi.org/10.1007/s10461-021-03179-y
State	Published - Oct 2021

Funding

The authors thank the entire RADAR research team, particularly Dr. Thomas Remble and Antonia Clifford for overseeing the project and Daniel T. Ryan for data management. The authors also thank the RADAR participants for sharing their experiences with them. This research was supported by a grant from the National Institute on Drug Abuse (U01DA036939; PI: Mustanski). The content of this article is solely the responsibility of the authors and does not necessarily reflect the views of the National Institutes of Health or the National Institute on Drug Abuse.

Keywords

Alcohol use
Drug use
HIV
Retention in care
Sexual and gender minorities
Substance use
Viral suppression

ASJC Scopus subject areas

Social Psychology
Public Health, Environmental and Occupational Health
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10461-021-03179-y

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abstract = "Retention in care and sustained viral suppression are integral outcomes in the care continuum for people living with HIV (PLWH) and HIV prevention; however, less is known about how substance use predicts sustained viral suppression over time. This study seeks to examine the predictive effects of substance use on sustained viral suppression in a sample of cisgender sexual minority men and gender minority PLWH (n = 163) drawn from a longitudinal sample in the Chicago area collected 2015–2019. Using data from 3 visits separated by 6 months, participants were coded persistently detectable, inconsistently virally suppressed, and consistently virally suppressed (< 40 copies/mL at all visits). Multinomial logistic regressions were utilized. About 40% of participants had sustained viral suppression. In multinomial logistic regressions, CUDIT-R predicted persistent detectable status and stimulant use was associated with inconsistent viral suppression. Substance use may create challenges in achieving sustained viral suppression, which has important implications for care and prevention.",

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Substance Use Predicts Sustained Viral Suppression in a Community Cohort of Sexual and Gender Minority Youth Living with HIV

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

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