Substructure of keratohyalin granules of the epidermis as revealed by high resolution electron microscopy

Robert M. Lavker; A. Gedeon Matoltsy

doi:10.1016/S0022-5320(71)80012-6

Substructure of keratohyalin granules of the epidermis as revealed by high resolution electron microscopy

Robert M. Lavker^*, A. Gedeon Matoltsy

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

Keratohyalin granules from both human and rat epidermis were studied by high resolution electron microscopy. At high magnification (× 250 000), the dense mass in keratohyalin granules revealed a fine granular substructure consisting of particles with dimensions in the range of 13-35 Å, with an average value of 20 Å. It was concluded that this particulate material represented a specific differentiation product of epidermal cells, primarily responsible for keratohyalin granule formation.

Original language	English (US)
Pages (from-to)	575-581
Number of pages	7
Journal	Journal of Ultrasructure Research
Volume	35
Issue number	5-6
DOIs	https://doi.org/10.1016/S0022-5320(71)80012-6
State	Published - Jun 1971

ASJC Scopus subject areas

Anatomy
Molecular Biology

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10.1016/S0022-5320(71)80012-6

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title = "Substructure of keratohyalin granules of the epidermis as revealed by high resolution electron microscopy",

abstract = "Keratohyalin granules from both human and rat epidermis were studied by high resolution electron microscopy. At high magnification (× 250 000), the dense mass in keratohyalin granules revealed a fine granular substructure consisting of particles with dimensions in the range of 13-35 {\AA}, with an average value of 20 {\AA}. It was concluded that this particulate material represented a specific differentiation product of epidermal cells, primarily responsible for keratohyalin granule formation.",

author = "Lavker, {Robert M.} and Matoltsy, {A. Gedeon}",

note = "Funding Information: 1 This investigation was supported by research grant AM 05779 from the National Institute of Arthritis and Metabolic Diseases, United States Public Health Service.",

year = "1971",

month = jun,

doi = "10.1016/S0022-5320(71)80012-6",

language = "English (US)",

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journal = "Journal of Structural Biology",

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AU - Lavker, Robert M.

AU - Matoltsy, A. Gedeon

N1 - Funding Information: 1 This investigation was supported by research grant AM 05779 from the National Institute of Arthritis and Metabolic Diseases, United States Public Health Service.

PY - 1971/6

Y1 - 1971/6

N2 - Keratohyalin granules from both human and rat epidermis were studied by high resolution electron microscopy. At high magnification (× 250 000), the dense mass in keratohyalin granules revealed a fine granular substructure consisting of particles with dimensions in the range of 13-35 Å, with an average value of 20 Å. It was concluded that this particulate material represented a specific differentiation product of epidermal cells, primarily responsible for keratohyalin granule formation.

AB - Keratohyalin granules from both human and rat epidermis were studied by high resolution electron microscopy. At high magnification (× 250 000), the dense mass in keratohyalin granules revealed a fine granular substructure consisting of particles with dimensions in the range of 13-35 Å, with an average value of 20 Å. It was concluded that this particulate material represented a specific differentiation product of epidermal cells, primarily responsible for keratohyalin granule formation.

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ER -

Substructure of keratohyalin granules of the epidermis as revealed by high resolution electron microscopy

Abstract

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