Successful medical management of a neonate with spontaneous splenic rupture and severe hemophilia A

Sherif M Badawy*, Jenna Rossoff, Sushmita G Yallapragada, Robert I Liem, Anjali A. Sharathkumar

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Scopus citations


Splenic rupture in neonates is a rare event, usually occurring in the setting of underlying predisposing conditions. Here, we present the case of a term neonate who presented with worsening anemia in the setting of known hemolytic disease during the newborn period and was later found to have a spontaneous splenic rupture. He was subsequently diagnosed with severe hemophilia A, and was managed medically with recombinant factor VIII replacement therapy without any surgical intervention. This is the first reported case of a neonate who had spontaneous splenic rupture and severe hemophilia A, and underwent successful medical treatment without any surgical intervention.

Original languageEnglish (US)
Pages (from-to)29-32
Number of pages4
JournalHematology/ Oncology and Stem Cell Therapy
Issue number1
StatePublished - Mar 1 2017



  • Factor VIII deficiency
  • Hemophilia A
  • Neonate
  • Splenic rupture

ASJC Scopus subject areas

  • Hematology
  • Oncology

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