Sudden cardiac death in heart failure with preserved ejection fraction: a target for therapy?

Muthiah Vaduganathan; Ravi B. Patel; Sanjiv J. Shah; Javed Butler

doi:10.1007/s10741-016-9525-z

Sudden cardiac death in heart failure with preserved ejection fraction: a target for therapy?

Muthiah Vaduganathan^*, Ravi B. Patel, Sanjiv J. Shah, Javed Butler

^*Corresponding author for this work

Medicine, Cardiology Division

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

The incidence and mechanisms of sudden cardiac death (SCD) among patients with heart failure with reduced ejection fraction have been well characterized. Conversely, limited data are available exploring the landscape of SCD in patients with heart failure with preserved ejection fraction (HFpEF). HFpEF is a heterogeneous clinical syndrome of increasing prevalence and is associated with substantial morbidity and mortality. This review will aim to contextualize recent data regarding rates and predictors of SCD in this growing population and to discuss the potential role of pharmacologic and device therapy for prevention of SCD within the at-risk HFpEF subset.

Original language	English (US)
Pages (from-to)	455-462
Number of pages	8
Journal	Heart Failure Reviews
Volume	21
Issue number	4
DOIs	https://doi.org/10.1007/s10741-016-9525-z
State	Published - Jul 1 2016

Keywords

Arrhythmias
Heart failure with preserved ejection fraction
Sudden cardiac death

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1007/s10741-016-9525-z

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title = "Sudden cardiac death in heart failure with preserved ejection fraction: a target for therapy?",

abstract = "The incidence and mechanisms of sudden cardiac death (SCD) among patients with heart failure with reduced ejection fraction have been well characterized. Conversely, limited data are available exploring the landscape of SCD in patients with heart failure with preserved ejection fraction (HFpEF). HFpEF is a heterogeneous clinical syndrome of increasing prevalence and is associated with substantial morbidity and mortality. This review will aim to contextualize recent data regarding rates and predictors of SCD in this growing population and to discuss the potential role of pharmacologic and device therapy for prevention of SCD within the at-risk HFpEF subset.",

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AU - Butler, Javed

PY - 2016/7/1

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N2 - The incidence and mechanisms of sudden cardiac death (SCD) among patients with heart failure with reduced ejection fraction have been well characterized. Conversely, limited data are available exploring the landscape of SCD in patients with heart failure with preserved ejection fraction (HFpEF). HFpEF is a heterogeneous clinical syndrome of increasing prevalence and is associated with substantial morbidity and mortality. This review will aim to contextualize recent data regarding rates and predictors of SCD in this growing population and to discuss the potential role of pharmacologic and device therapy for prevention of SCD within the at-risk HFpEF subset.

AB - The incidence and mechanisms of sudden cardiac death (SCD) among patients with heart failure with reduced ejection fraction have been well characterized. Conversely, limited data are available exploring the landscape of SCD in patients with heart failure with preserved ejection fraction (HFpEF). HFpEF is a heterogeneous clinical syndrome of increasing prevalence and is associated with substantial morbidity and mortality. This review will aim to contextualize recent data regarding rates and predictors of SCD in this growing population and to discuss the potential role of pharmacologic and device therapy for prevention of SCD within the at-risk HFpEF subset.

KW - Arrhythmias

KW - Heart failure with preserved ejection fraction

KW - Sudden cardiac death

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Sudden cardiac death in heart failure with preserved ejection fraction: a target for therapy?

Abstract

Keywords

ASJC Scopus subject areas

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