Sudden Death in Bundle-Branch Block

Max Michael, Kenneth M. Rosen, Pablo Denes, Ramesh Dhingra, Christopher Wyndham, John H. Mcanulty, Shahbudin H. Rahimtoola, Edward S. Murphy, Leonard W. Ritzmann, Paula Kanarek, Henry Demots

Research output: Contribution to journalLetterpeer-review


To the Editor: The report by McAnulty et al. of their prospective study of bundle-branch-block in the August 3 issue of the Journal demonstrates an epidemiologic flaw that could modify the study results and its implications. For the 1211 abnormal electrocardiograms meeting the authors' criteria the authors got in touch with 638 patients as part of the study protocol. Only half the population at risk was studied. The demographic characteristics of the patients lost to follow-up observation are not available to determine the potential effect of selection bias. The problems of a large, prospective study are formidable, but size and…

Original languageEnglish (US)
Pages (from-to)1256-1257
Number of pages2
JournalNew England Journal of Medicine
Issue number22
StatePublished - Nov 30 1978

ASJC Scopus subject areas

  • General Medicine


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