Sudden Death in Patients With Chronic Bifascicular Block

Pablo Denes*, Ramesh C. Dhingra, Delon Wu, Christopher R. Wyndham, Fernando Amat-y-Leon, Kenneth M. Rosen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

79 Scopus citations


Prospective follow-up studies of 277 patients with chronic bifascicular block showed that 30 patients developed sudden cardiac death (SCD). Cumulative one-, two-, and three-year SCD mortality was computed. The patients that developed SCD were compared with the remaining patients (209 alive and 38 dead). The groups were similar in regard to age, sex, AH, and HV intervals. The following were more frequent in the SCD group (P <.05): angina, previous myocardial infarction, heart failure, cardiomegaly, left bundle-branch block, premature ventricular beats, and ventricular tachycardia. Ventricular fibrillation was the cause of death in four cases of SCD where terminal ECG documentation was available. We concluded that SCD is a major cause of mortality in patients with chronic bifascicular block. The association of SCD with coronary disease and ventricular dysrhythmia suggested ventricular fibrillation as a frequent mechanism.

Original languageEnglish (US)
Pages (from-to)1005-1010
Number of pages6
JournalArchives of Internal Medicine
Issue number8
StatePublished - Aug 1977

ASJC Scopus subject areas

  • Internal Medicine


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