Sudden onset blindness in sickle cell disease due to retinal artery occlusion

Robert I Liem*, Diane M. Calamaras, Manpreet S. Chhabra, Beatrice Files, Caterina P. Minniti, Alexis A Thompson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Central retinal artery occlusion (CRAO) is a rare and potentially devastating cause of acute blindness in sickle cell disease (SCD) that is unique compared to classic sickle retinopathy. Few details related to this complication in SCD are known, including its risk factors, pathogenesis, presentation, treatment and outcomes. We present three patients with SCD and retinal artery occlusion. The overall variability in clinical presentation, treatment and prognosis reported in the literature underscores the need for a greater understanding of these factors as they relate to this complication in SCD.

Original languageEnglish (US)
Pages (from-to)624-627
Number of pages4
JournalPediatric Blood and Cancer
Issue number3
StatePublished - Mar 1 2008


  • Macular ischemia
  • Retinal artery occlusion
  • Sickle cell disease
  • Sudden blindness

ASJC Scopus subject areas

  • Cancer Research
  • Pediatrics, Perinatology, and Child Health
  • Hematology


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