Vorschlag für eine neue patientenorientierte Epilepsieklassifikation

Translated title of the contribution: Suggestion for a new, patient-oriented epilepsy classification

C. Kellinghaus*, T. Loddenkemper, E. Wyllie, I. Najm, A. Gupta, F. Rosenow, C. Baumgartner, F. Boesebeck, B. Diehl, C. Drees, A. Ebner, H. Hamer, S. Knake, J. H. Meencke, M. Merschhemke, G. Möddel, S. Noachtar, S. Rona, S. U. Schuele, B. J. SteinhoffI. Tuxhorn, K. Werhahn, H. O. Lüders

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The recent proposal by the ILAE Task Force for Epilepsy Classification is a multiaxial, syndrome-oriented approach. Epilepsy syndromes - at least as defined by the ILAE Task Force - group patients according to multiple, usually poorly defined parameters. As a result, these syndromes frequently show significant overlap and may change with patient age. We propose a five-dimensional and patient-oriented approach to epilepsy classification. This approach shifts away from syndrome orientation, using independent criteria in each of the five dimensions similarly to the diagnostic process in general neurology. The main dimensions of this new classification consist of (1) localizing the epileptogenic zone, (2) semiology of the seizure, (3) etiology, (4) seizure frequency, and (5) related medical conditions. These dimensions characterize all information necessary for patient management, are independent parameters, and include information more pertinent than the ILAE axes with regard to patient management. All cases can be classified according to this five-dimensional system, even at initial encounter when no detailed test results are available. Information from clinical tests such as MRI and EEG are translated into the best possible working hypothesis at the time of classification, allowing increased precision of the classification as additional information becomes available.

Translated title of the contributionSuggestion for a new, patient-oriented epilepsy classification
Original languageGerman
Pages (from-to)276-285
Number of pages10
JournalZeitschrift fur Epileptologie
Volume19
Issue number4
DOIs
StatePublished - Nov 1 2006

Keywords

  • Epilepsy classification
  • Epilepsy syndrome
  • ILAE
  • Medical factors
  • Patient orientation
  • Syndrome orientation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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