SUNCT syndrome: Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing

Patrick Alore, Walter Jay, Mícheál Macken*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The SUNCT syndrome refers to Short-lasting Unilateral Neuralgiform headache with Conjunctival injection and Tearing. It is characterized by brief attacks of severe unilateral pain in the orbitotemporal region, associated with ipsilateral cranial autonomic disturbances. All SUNCT patients experience ipsilateral conjunctival injection and lacrimation. Mean age of onset is 50 years with a male predominance. The syndrome is often misdiagnosed as trigeminal neuralgia or cluster headache. Primary and secondary forms exist, the secondary form is most commonly associated with lesions of the posterior fossa or pituitary adenoma. The SUNCT syndrome is refractory to most commonly employed therapies. Lamotrigine has recently been reported as an effective first line therapy.

Original languageEnglish (US)
Pages (from-to)9-13
Number of pages5
JournalSeminars in Ophthalmology
Volume21
Issue number1
DOIs
StatePublished - Jan 1 2006

Keywords

  • International Headache Society (IHS)
  • Lamotrigine
  • SUNCT syndrome
  • Trigeminal Autonomic Cephalgias (TACs)
  • short-lasting headache

ASJC Scopus subject areas

  • Ophthalmology

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