18F-NaF PET/CT in extensive melorheostosis of the axial and appendicular skeleton with soft-tissue involvement

Georgios Z. Papadakis*, Smita Jha, Timothy Bhattacharyya, Corina Millo, Tsang Wei Tu, Ulas Bagci, Kostas Marias, Apostolos H. Karantanas, Nicholas J. Patronas

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Melorheostosis is a rare, nonhereditary, benign, sclerotic bone dysplasia with no sex predilection, typically occurring in late childhood or early adulthood, which can lead to substantial functional morbidity, depending on the sites of involvement. We report on a patient with extensive melorheostosis in the axial and appendicular skeleton, as well as in the soft tissues, who was evaluated with whole-body 18F-NaF PET/CT scan. All melorheostotic lesions of the skeleton and of the ossified soft-tissue masses demonstrated intensely increased 18F-NaF activity, suggesting the application of this modality in assessing and monitoring the disease activity.

Original languageEnglish (US)
Pages (from-to)537-539
Number of pages3
JournalClinical nuclear medicine
Volume42
Issue number7
DOIs
StatePublished - Mar 17 2017
Externally publishedYes

Keywords

  • Bone dysplasia
  • F-NaF PET/CT
  • Melorheostosis
  • Osteosclerosis
  • Soft-tissue ossified masses

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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