1H NMR, EPR, UV-Vis, and Electrochemical Studies of Imidazole Complexes of Ru(III). Crystal Structures of cis-[(Im)2(NH3)4RuIII]Br3 and [(1MeIm)6RuII]Cl2·2H2O

M. J. Clarke*, V. M. Bailey, Peter E Doan, C. D. Hiller, K. J. LaChance-Galang, H. Daghlian, S. Mandal, C. M. Bastos, D. Lang

*Corresponding author for this work

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

Comparisons of the spectroscopic properties of a number of RuIII complexes of imidazole ligands provide methods of distinguishing between various types of bonding that can occur in proteins and nucleic acids. In particular, EPR and 1H NMR parameters arising from the paramagnetism of RuIII should aid in determining binding sites of RuIII drugs in macromolecules. Electrochemical studies on several imidazole complexes of ruthenium suggest that imidazole may serve as a significant π-acceptor ligand in the presence of anionic ligands. Crystal structures are reported on two active immunosuppressant complexes. cis-[(Im)2(NH3)4RuIII]Br3 crystallizes in the triclinic space group P1̄ (No. 2) with the cell parameters a = 8.961(2) Å, b = 12.677(3) Å, c = 7.630(2) Å, α = 98.03- (2)°, β = 100.68(2)°, γ = 81.59(2)°, and Z = 2 (R = 0.044). [(1MeIm)6RuII]Cl2·2H2O crystallizes in the monoclinic space group P21/n (No. 14) with the cell parameters a = 7.994(2) Å, b = 13.173(4) Å, c = 14.904(2) Å, β = 97.89(1)°, and Z = 2 (R = 0.052). The average RuII-N bond distance is 2.106(8) Å.

Original languageEnglish (US)
Pages (from-to)4896-4903
Number of pages8
JournalInorganic chemistry
Volume35
Issue number17
StatePublished - Dec 1 1996

Fingerprint

imidazoles
Paramagnetic resonance
Crystal structure
Nuclear magnetic resonance
Ligands
nuclear magnetic resonance
ligands
crystal structure
Paramagnetism
Ruthenium
paramagnetism
nucleic acids
Immunosuppressive Agents
cells
Macromolecules
macromolecules
Nucleic Acids
ruthenium
drugs
Binding Sites

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry

Cite this

Clarke, M. J. ; Bailey, V. M. ; Doan, Peter E ; Hiller, C. D. ; LaChance-Galang, K. J. ; Daghlian, H. ; Mandal, S. ; Bastos, C. M. ; Lang, D. / 1H NMR, EPR, UV-Vis, and Electrochemical Studies of Imidazole Complexes of Ru(III). Crystal Structures of cis-[(Im)2(NH3)4RuIII]Br3 and [(1MeIm)6RuII]Cl2·2H2O. In: Inorganic chemistry. 1996 ; Vol. 35, No. 17. pp. 4896-4903.
@article{7c7c59559a464a56895d1978a7be275c,
title = "1H NMR, EPR, UV-Vis, and Electrochemical Studies of Imidazole Complexes of Ru(III). Crystal Structures of cis-[(Im)2(NH3)4RuIII]Br3 and [(1MeIm)6RuII]Cl2·2H2O",
abstract = "Comparisons of the spectroscopic properties of a number of RuIII complexes of imidazole ligands provide methods of distinguishing between various types of bonding that can occur in proteins and nucleic acids. In particular, EPR and 1H NMR parameters arising from the paramagnetism of RuIII should aid in determining binding sites of RuIII drugs in macromolecules. Electrochemical studies on several imidazole complexes of ruthenium suggest that imidazole may serve as a significant π-acceptor ligand in the presence of anionic ligands. Crystal structures are reported on two active immunosuppressant complexes. cis-[(Im)2(NH3)4RuIII]Br3 crystallizes in the triclinic space group P1̄ (No. 2) with the cell parameters a = 8.961(2) {\AA}, b = 12.677(3) {\AA}, c = 7.630(2) {\AA}, α = 98.03- (2)°, β = 100.68(2)°, γ = 81.59(2)°, and Z = 2 (R = 0.044). [(1MeIm)6RuII]Cl2·2H2O crystallizes in the monoclinic space group P21/n (No. 14) with the cell parameters a = 7.994(2) {\AA}, b = 13.173(4) {\AA}, c = 14.904(2) {\AA}, β = 97.89(1)°, and Z = 2 (R = 0.052). The average RuII-N bond distance is 2.106(8) {\AA}.",
author = "Clarke, {M. J.} and Bailey, {V. M.} and Doan, {Peter E} and Hiller, {C. D.} and LaChance-Galang, {K. J.} and H. Daghlian and S. Mandal and Bastos, {C. M.} and D. Lang",
year = "1996",
month = "12",
day = "1",
language = "English (US)",
volume = "35",
pages = "4896--4903",
journal = "Inorganic Chemistry",
issn = "0020-1669",
publisher = "American Chemical Society",
number = "17",

}

Clarke, MJ, Bailey, VM, Doan, PE, Hiller, CD, LaChance-Galang, KJ, Daghlian, H, Mandal, S, Bastos, CM & Lang, D 1996, '1H NMR, EPR, UV-Vis, and Electrochemical Studies of Imidazole Complexes of Ru(III). Crystal Structures of cis-[(Im)2(NH3)4RuIII]Br3 and [(1MeIm)6RuII]Cl2·2H2O', Inorganic chemistry, vol. 35, no. 17, pp. 4896-4903.

1H NMR, EPR, UV-Vis, and Electrochemical Studies of Imidazole Complexes of Ru(III). Crystal Structures of cis-[(Im)2(NH3)4RuIII]Br3 and [(1MeIm)6RuII]Cl2·2H2O. / Clarke, M. J.; Bailey, V. M.; Doan, Peter E; Hiller, C. D.; LaChance-Galang, K. J.; Daghlian, H.; Mandal, S.; Bastos, C. M.; Lang, D.

In: Inorganic chemistry, Vol. 35, No. 17, 01.12.1996, p. 4896-4903.

Research output: Contribution to journalArticle

TY - JOUR

T1 - 1H NMR, EPR, UV-Vis, and Electrochemical Studies of Imidazole Complexes of Ru(III). Crystal Structures of cis-[(Im)2(NH3)4RuIII]Br3 and [(1MeIm)6RuII]Cl2·2H2O

AU - Clarke, M. J.

AU - Bailey, V. M.

AU - Doan, Peter E

AU - Hiller, C. D.

AU - LaChance-Galang, K. J.

AU - Daghlian, H.

AU - Mandal, S.

AU - Bastos, C. M.

AU - Lang, D.

PY - 1996/12/1

Y1 - 1996/12/1

N2 - Comparisons of the spectroscopic properties of a number of RuIII complexes of imidazole ligands provide methods of distinguishing between various types of bonding that can occur in proteins and nucleic acids. In particular, EPR and 1H NMR parameters arising from the paramagnetism of RuIII should aid in determining binding sites of RuIII drugs in macromolecules. Electrochemical studies on several imidazole complexes of ruthenium suggest that imidazole may serve as a significant π-acceptor ligand in the presence of anionic ligands. Crystal structures are reported on two active immunosuppressant complexes. cis-[(Im)2(NH3)4RuIII]Br3 crystallizes in the triclinic space group P1̄ (No. 2) with the cell parameters a = 8.961(2) Å, b = 12.677(3) Å, c = 7.630(2) Å, α = 98.03- (2)°, β = 100.68(2)°, γ = 81.59(2)°, and Z = 2 (R = 0.044). [(1MeIm)6RuII]Cl2·2H2O crystallizes in the monoclinic space group P21/n (No. 14) with the cell parameters a = 7.994(2) Å, b = 13.173(4) Å, c = 14.904(2) Å, β = 97.89(1)°, and Z = 2 (R = 0.052). The average RuII-N bond distance is 2.106(8) Å.

AB - Comparisons of the spectroscopic properties of a number of RuIII complexes of imidazole ligands provide methods of distinguishing between various types of bonding that can occur in proteins and nucleic acids. In particular, EPR and 1H NMR parameters arising from the paramagnetism of RuIII should aid in determining binding sites of RuIII drugs in macromolecules. Electrochemical studies on several imidazole complexes of ruthenium suggest that imidazole may serve as a significant π-acceptor ligand in the presence of anionic ligands. Crystal structures are reported on two active immunosuppressant complexes. cis-[(Im)2(NH3)4RuIII]Br3 crystallizes in the triclinic space group P1̄ (No. 2) with the cell parameters a = 8.961(2) Å, b = 12.677(3) Å, c = 7.630(2) Å, α = 98.03- (2)°, β = 100.68(2)°, γ = 81.59(2)°, and Z = 2 (R = 0.044). [(1MeIm)6RuII]Cl2·2H2O crystallizes in the monoclinic space group P21/n (No. 14) with the cell parameters a = 7.994(2) Å, b = 13.173(4) Å, c = 14.904(2) Å, β = 97.89(1)°, and Z = 2 (R = 0.052). The average RuII-N bond distance is 2.106(8) Å.

UR - http://www.scopus.com/inward/record.url?scp=0001663293&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0001663293&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0001663293

VL - 35

SP - 4896

EP - 4903

JO - Inorganic Chemistry

JF - Inorganic Chemistry

SN - 0020-1669

IS - 17

ER -