1H NMR, EPR, UV-Vis, and Electrochemical Studies of Imidazole Complexes of Ru(III). Crystal Structures of cis-[(Im)2(NH3)4RuIII]Br3 and [(1MeIm)6RuII]Cl2·2H2O

M. J. Clarke*, V. M. Bailey, Peter E Doan, C. D. Hiller, K. J. LaChance-Galang, H. Daghlian, S. Mandal, C. M. Bastos, D. Lang

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Abstract

Comparisons of the spectroscopic properties of a number of RuIII complexes of imidazole ligands provide methods of distinguishing between various types of bonding that can occur in proteins and nucleic acids. In particular, EPR and 1H NMR parameters arising from the paramagnetism of RuIII should aid in determining binding sites of RuIII drugs in macromolecules. Electrochemical studies on several imidazole complexes of ruthenium suggest that imidazole may serve as a significant π-acceptor ligand in the presence of anionic ligands. Crystal structures are reported on two active immunosuppressant complexes. cis-[(Im)2(NH3)4RuIII]Br3 crystallizes in the triclinic space group P1̄ (No. 2) with the cell parameters a = 8.961(2) Å, b = 12.677(3) Å, c = 7.630(2) Å, α = 98.03- (2)°, β = 100.68(2)°, γ = 81.59(2)°, and Z = 2 (R = 0.044). [(1MeIm)6RuII]Cl2·2H2O crystallizes in the monoclinic space group P21/n (No. 14) with the cell parameters a = 7.994(2) Å, b = 13.173(4) Å, c = 14.904(2) Å, β = 97.89(1)°, and Z = 2 (R = 0.052). The average RuII-N bond distance is 2.106(8) Å.

Original languageEnglish (US)
Pages (from-to)4896-4903
Number of pages8
JournalInorganic chemistry
Volume35
Issue number17
StatePublished - Dec 1 1996

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ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry

Cite this

Clarke, M. J., Bailey, V. M., Doan, P. E., Hiller, C. D., LaChance-Galang, K. J., Daghlian, H., Mandal, S., Bastos, C. M., & Lang, D. (1996). 1H NMR, EPR, UV-Vis, and Electrochemical Studies of Imidazole Complexes of Ru(III). Crystal Structures of cis-[(Im)2(NH3)4RuIII]Br3 and [(1MeIm)6RuII]Cl2·2H2O. Inorganic chemistry, 35(17), 4896-4903.