90Y Liver Radioembolization Imaging Using Amplitude-Based Gated PET/CT

Dustin R. Osborne*, Shelley Acuff, Melissa Neveu, Austin Kaman, Mumtaz Syed, Yitong Fu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The usage of PET/CT to monitor patients with hepatocellular carcinoma following 90 Y radioembolization has increased; however, image quality is often poor because of low count efficiency and respiratory motion. Motion can be corrected using gating techniques but at the expense of additional image noise. Amplitude-based gating has been shown to improve quantification in FDG PET, but few have used this technique in 90 Y liver imaging. The patients shown in this work indicate that amplitude-based gating can be used in 90 Y PET/CT liver imaging to provide motion-corrected images with higher estimates of activity concentration that may improve posttherapy dosimetry.

Original languageEnglish (US)
Pages (from-to)373-374
Number of pages2
JournalClinical nuclear medicine
Volume42
Issue number5
DOIs
StatePublished - May 1 2017

Keywords

  • 90 Y dosimetry
  • PET/CT
  • gating
  • motion correction
  • radioembolization
  • yttrium

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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