Superior sagittal sinus thrombosis in a patient with postdural puncture headache

Honorio T. Benzon*, Muhammad Iqbal, Martin S. Tallman, Larry Boehlke, Eric J. Russell

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Background and Objective: The occurrence of concomitant intracranial pathology in a patient with postdural puncture headache (PDPH) is rare. We present a patient who had a superior sagittal sinus thrombosis in addition to his PDPH. The signs and symptoms of intracranial pathology in patients with dural puncture headache, in addition to their postural headache, are discussed. Case Report: A 32-year-old man with lymphoblastic lymphoma received treatment with daunorubicin, vincristine, and prednisone. He developed postural headache and severe nausea and vomiting after a diagnostic lumbar puncture. Magnetic resonance imaging (MRI) showed superior sagittal sinus (SSS) thrombosis and meningeal enhancement. An epidural blood patch was performed and enoxaparin was prescribed for 6 months. He has remained asymptomatic. Conclusions: Patients with PDPH have classic postural headache. The occurrence of additional signs and symptoms should alert the clinician to the presence of intracranial pathology. Patients with lymphoblastic lymphoma who had treatment with L-asparaginase and steroid are predisposed to the development of cortical venous thrombosis and may have this syndrome in addition to a dural puncture headache.

Original languageEnglish (US)
Pages (from-to)64-67
Number of pages4
JournalRegional Anesthesia and Pain Medicine
Issue number1
StatePublished - Jan 1 2003


  • Cephalalgia
  • Clot
  • Dural venous sinus
  • Postural

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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