TY - JOUR
T1 - Support for a postresection prognostic score for pancreatic endocrine tumors
AU - Hurtuk, Michael G.
AU - Godambe, Anjali S.
AU - Shoup, Margo
AU - Yong, Sherri
AU - Aranha, Gerard V.
PY - 2011/3
Y1 - 2011/3
N2 - Background: Prognostic scores predicting long-term survival of patients with pancreatic neuroendocrine tumors (PNETs) have been created. The purpose of this study was to validate a prognostic scoring scheme at a single institution. Methods: We reviewed all resections for PNETs from 1996 to 2004. Prognostic scores based on patient age, tumor grade, and distant metastasis were calculated. Survival was compared with an established postresection prognostic score for PNETs. Results: A total of 34 PNETs were identified. Predicted 5-year survival for prognostic scores of 1, 2, and 3 were 76.7%, 50.9%, and 35.7%, respectively. Final prognostic scores of 1, 2, and 3 were observed in 13 (38%), 18 (53%), and 3 (9%) patients, with observed actual 5-year survivals of 92.3%, 72.2%, and 66.7%, respectively. Conclusions: PNET prognostic scores were found to be inversely related to survival. PNET postresection prognostic score categories may be useful tools in predicting long-term survival.
AB - Background: Prognostic scores predicting long-term survival of patients with pancreatic neuroendocrine tumors (PNETs) have been created. The purpose of this study was to validate a prognostic scoring scheme at a single institution. Methods: We reviewed all resections for PNETs from 1996 to 2004. Prognostic scores based on patient age, tumor grade, and distant metastasis were calculated. Survival was compared with an established postresection prognostic score for PNETs. Results: A total of 34 PNETs were identified. Predicted 5-year survival for prognostic scores of 1, 2, and 3 were 76.7%, 50.9%, and 35.7%, respectively. Final prognostic scores of 1, 2, and 3 were observed in 13 (38%), 18 (53%), and 3 (9%) patients, with observed actual 5-year survivals of 92.3%, 72.2%, and 66.7%, respectively. Conclusions: PNET prognostic scores were found to be inversely related to survival. PNET postresection prognostic score categories may be useful tools in predicting long-term survival.
KW - Pancreatic endocrine Tumor
KW - Prognostic score
UR - http://www.scopus.com/inward/record.url?scp=79952132906&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79952132906&partnerID=8YFLogxK
U2 - 10.1016/j.amjsurg.2010.09.023
DO - 10.1016/j.amjsurg.2010.09.023
M3 - Article
C2 - 21367388
AN - SCOPUS:79952132906
SN - 0002-9610
VL - 201
SP - 406
EP - 410
JO - American journal of surgery
JF - American journal of surgery
IS - 3
ER -