Suppression of growth of L cells in suspension culture by dibutyryl adenosine 3′,5′-monophosphate

Albert Oler*, Philip M. Iannaccone, Gerald B. Gordon

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

The growth of L cells in suspension cultures as determined by cell count and protein measurement is markedly reduced by the addition of dibutyryl cyclic adenosine 3′,5′-monophosphate (AMP) and theophylline to the culture flasks. Following the transfer of these cells to normal media the effect of dibutyryl cyclic AMP on cell growth lasts between 24 and 48 hr, and afterwards the cells have normal growth Growth arrested L cells remain agglutinable by wheat germ agglutinin.

Original languageEnglish (US)
Pages (from-to)35-38
Number of pages4
JournalIn Vitro
Volume9
Issue number1
DOIs
StatePublished - Jul 1 1973

ASJC Scopus subject areas

  • Biotechnology
  • Plant Science

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