Suppression of growth of L cells in suspension culture by dibutyryl adenosine 3′,5′-monophosphate

Albert Oler; Philip M. Iannaccone; Gerald B. Gordon

doi:10.1007/BF02615987

Suppression of growth of L cells in suspension culture by dibutyryl adenosine 3′,5′-monophosphate

Albert Oler^*, Philip M. Iannaccone, Gerald B. Gordon

^*Corresponding author for this work

Pediatrics

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16 Scopus citations

Abstract

The growth of L cells in suspension cultures as determined by cell count and protein measurement is markedly reduced by the addition of dibutyryl cyclic adenosine 3′,5′-monophosphate (AMP) and theophylline to the culture flasks. Following the transfer of these cells to normal media the effect of dibutyryl cyclic AMP on cell growth lasts between 24 and 48 hr, and afterwards the cells have normal growth Growth arrested L cells remain agglutinable by wheat germ agglutinin.

Original language	English (US)
Pages (from-to)	35-38
Number of pages	4
Journal	In Vitro
Volume	9
Issue number	1
DOIs	https://doi.org/10.1007/BF02615987
State	Published - Jul 1 1973

ASJC Scopus subject areas

Biotechnology
Plant Science

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abstract = "The growth of L cells in suspension cultures as determined by cell count and protein measurement is markedly reduced by the addition of dibutyryl cyclic adenosine 3′,5′-monophosphate (AMP) and theophylline to the culture flasks. Following the transfer of these cells to normal media the effect of dibutyryl cyclic AMP on cell growth lasts between 24 and 48 hr, and afterwards the cells have normal growth Growth arrested L cells remain agglutinable by wheat germ agglutinin.",

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AU - Oler, Albert

AU - Iannaccone, Philip M.

AU - Gordon, Gerald B.

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N2 - The growth of L cells in suspension cultures as determined by cell count and protein measurement is markedly reduced by the addition of dibutyryl cyclic adenosine 3′,5′-monophosphate (AMP) and theophylline to the culture flasks. Following the transfer of these cells to normal media the effect of dibutyryl cyclic AMP on cell growth lasts between 24 and 48 hr, and afterwards the cells have normal growth Growth arrested L cells remain agglutinable by wheat germ agglutinin.

AB - The growth of L cells in suspension cultures as determined by cell count and protein measurement is markedly reduced by the addition of dibutyryl cyclic adenosine 3′,5′-monophosphate (AMP) and theophylline to the culture flasks. Following the transfer of these cells to normal media the effect of dibutyryl cyclic AMP on cell growth lasts between 24 and 48 hr, and afterwards the cells have normal growth Growth arrested L cells remain agglutinable by wheat germ agglutinin.

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Suppression of growth of L cells in suspension culture by dibutyryl adenosine 3′,5′-monophosphate

Abstract

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