Suppression of sympathetic nervous system during fasting

James B. Young; Lewis Landsberg

doi:10.1002/j.1550-8528.1997.tb00590.x

Suppression of sympathetic nervous system during fasting

James B. Young^*, Lewis Landsberg

^*Corresponding author for this work

Medicine, Endocrinology Division

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24 Scopus citations

Abstract

Two days of fasting in rats significantly reduces the turnover of norepinephrine in the heart. In contrast to the effects of ganglionic blockade in fed controls, similar blockade in fasted animals is without significant effect on [³H]-norepinephrine retention or endogenous norepinephrine in the heart. These data are consistent with suppression of centrally mediated sympathetic activity in the fasted state. The decrease in norepinephrine turnover during fasting is completely reversed by 1 day of refeeding.

Original language	English (US)
Pages (from-to)	646-649
Number of pages	4
Journal	Obesity Research
Volume	5
Issue number	6
DOIs	https://doi.org/10.1002/j.1550-8528.1997.tb00590.x
State	Published - 1997

ASJC Scopus subject areas

Medicine (miscellaneous)
Food Science
Endocrinology, Diabetes and Metabolism
Endocrinology
Public Health, Environmental and Occupational Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/j.1550-8528.1997.tb00590.x

Cite this

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title = "Suppression of sympathetic nervous system during fasting",

abstract = "Two days of fasting in rats significantly reduces the turnover of norepinephrine in the heart. In contrast to the effects of ganglionic blockade in fed controls, similar blockade in fasted animals is without significant effect on [3H]-norepinephrine retention or endogenous norepinephrine in the heart. These data are consistent with suppression of centrally mediated sympathetic activity in the fasted state. The decrease in norepinephrine turnover during fasting is completely reversed by 1 day of refeeding.",

author = "Young, {James B.} and Lewis Landsberg",

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AU - Landsberg, Lewis

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AB - Two days of fasting in rats significantly reduces the turnover of norepinephrine in the heart. In contrast to the effects of ganglionic blockade in fed controls, similar blockade in fasted animals is without significant effect on [3H]-norepinephrine retention or endogenous norepinephrine in the heart. These data are consistent with suppression of centrally mediated sympathetic activity in the fasted state. The decrease in norepinephrine turnover during fasting is completely reversed by 1 day of refeeding.

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Suppression of sympathetic nervous system during fasting

Abstract

ASJC Scopus subject areas

UN SDGs

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