Suppressive effects of regional lymph node cells and extracts on antibody- dependent cellular cytotoxicity

W. J. Catalona, A. T. Feldman, T. L. Ratliff, R. E. McCool

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Lymphocytes from regional lymph nodes that drain tumors and extracts of such lymphocytes suppress antibody-dependent cell-mediated target cell lysis by effector cells from cancer patients and controls. In contrast, lymph node cells from control patients are not suppressive. Control extracts from normal lymphocytes and 2 immunologically inert tissues, muscle and kidney, exhibit some suppressive activity but significantly less than extracts from lymph nodes that drain tumors.

Original languageEnglish (US)
Pages (from-to)396-402
Number of pages7
JournalJournal of Urology
Volume119
Issue number3
DOIs
StatePublished - Jan 1 1978

ASJC Scopus subject areas

  • Urology

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