Suprachiasmatic Nucleus (SCN)

Phyllis C Zee; Roneil Gopal Malkani; N. Dang

doi:10.1016/B978-0-12-385157-4.00578-9

Suprachiasmatic Nucleus (SCN)

Phyllis C Zee^*, Roneil Gopal Malkani, N. Dang

^*Corresponding author for this work

Neurology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The suprachiasmatic nucleus (SCN) regulates daily rhythms of nearly all physiological and behavioral processes. Pacemaker activity in the SCN arises from the synchronized activity of multiple single-cell circadian oscillators that are regulated at the molecular level, generating a near 24-h rhythm that is synchronized to the environmental light/dark cycle by light and nonphotic stimuli. The SCN primarily communicates rhythmic information to other brain regions and peripheral tissues via projections to other hypothalamic regions involved in the regulation of physiology and behavior, including sleep and wakefulness, autonomic function, cognition, metabolism, and pineal melatonin secretion.

Original language	English (US)
Title of host publication	Encyclopedia of the Neurological Sciences
Publisher	Elsevier Inc
Pages	355-356
Number of pages	2
ISBN (Electronic)	9780123851574
ISBN (Print)	9780123851581
DOIs	https://doi.org/10.1016/B978-0-12-385157-4.00578-9
State	Published - Jan 1 2014

Keywords

Circadian rhythm
Hypothalamus
Light
Melanopsin
Melatonin
Pineal
Retinohypothalamic tract
Sleep
Subparaventricular zone
Suprachiasmatic nucleus

ASJC Scopus subject areas

General Medicine

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10.1016/B978-0-12-385157-4.00578-9

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abstract = "The suprachiasmatic nucleus (SCN) regulates daily rhythms of nearly all physiological and behavioral processes. Pacemaker activity in the SCN arises from the synchronized activity of multiple single-cell circadian oscillators that are regulated at the molecular level, generating a near 24-h rhythm that is synchronized to the environmental light/dark cycle by light and nonphotic stimuli. The SCN primarily communicates rhythmic information to other brain regions and peripheral tissues via projections to other hypothalamic regions involved in the regulation of physiology and behavior, including sleep and wakefulness, autonomic function, cognition, metabolism, and pineal melatonin secretion.",

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AU - Malkani, Roneil Gopal

AU - Dang, N.

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N2 - The suprachiasmatic nucleus (SCN) regulates daily rhythms of nearly all physiological and behavioral processes. Pacemaker activity in the SCN arises from the synchronized activity of multiple single-cell circadian oscillators that are regulated at the molecular level, generating a near 24-h rhythm that is synchronized to the environmental light/dark cycle by light and nonphotic stimuli. The SCN primarily communicates rhythmic information to other brain regions and peripheral tissues via projections to other hypothalamic regions involved in the regulation of physiology and behavior, including sleep and wakefulness, autonomic function, cognition, metabolism, and pineal melatonin secretion.

AB - The suprachiasmatic nucleus (SCN) regulates daily rhythms of nearly all physiological and behavioral processes. Pacemaker activity in the SCN arises from the synchronized activity of multiple single-cell circadian oscillators that are regulated at the molecular level, generating a near 24-h rhythm that is synchronized to the environmental light/dark cycle by light and nonphotic stimuli. The SCN primarily communicates rhythmic information to other brain regions and peripheral tissues via projections to other hypothalamic regions involved in the regulation of physiology and behavior, including sleep and wakefulness, autonomic function, cognition, metabolism, and pineal melatonin secretion.

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KW - Hypothalamus

KW - Light

KW - Melanopsin

KW - Melatonin

KW - Pineal

KW - Retinohypothalamic tract

KW - Sleep

KW - Subparaventricular zone

KW - Suprachiasmatic nucleus

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ER -

Suprachiasmatic Nucleus (SCN)

Abstract

Keywords

ASJC Scopus subject areas

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