TY - JOUR
T1 - Supraesophageal reflux
T2 - Validation of a symptom questionnaire
AU - Dauer, E.
AU - Thompson, D.
AU - Zinsmeister, A. R.
AU - Dierkhising, R.
AU - Harris, A.
AU - Zais, T.
AU - Alexander, J.
AU - Murray, J. A.
AU - Wise, J. L.
AU - Lim, K.
AU - Locke, G. R.
AU - Romero, Yvonne
N1 - Funding Information:
This work was supported by an AstraZeneca Investigator Initiated Award.
PY - 2006/1
Y1 - 2006/1
N2 - OBJECTIVE: To develop and validate a questionnaire for supraesophageal manifestations of reflux (SER) that will facilitate its study in clinical and research settings. STUDY DESIGN: The Supraesophageal Reflux Questionnaire (SERQ) and previously validated Reflux Symptom Index (RSI) were subjected to multiple types of validity testing, including content validity, concurrent validity, reproducibility, and predictive validity. RESULTS: The concurrent validity and reproducibility of both instruments was good to excellent for most items tested. The predictive validity of the SERQ was superior to the RSI when it included the covariates of history of sinusitis, use of over-the-counter antacid medications, age, gender, and body mass index. CONCLUSIONS: The SERQ will serve as both a useful clinical and research tool by offering not only SER symptom information, like the RSI, but also information about the patient's medical history and medication usage that will facilitate use of the SERQ in research protocols. EBM rating: B-2b.
AB - OBJECTIVE: To develop and validate a questionnaire for supraesophageal manifestations of reflux (SER) that will facilitate its study in clinical and research settings. STUDY DESIGN: The Supraesophageal Reflux Questionnaire (SERQ) and previously validated Reflux Symptom Index (RSI) were subjected to multiple types of validity testing, including content validity, concurrent validity, reproducibility, and predictive validity. RESULTS: The concurrent validity and reproducibility of both instruments was good to excellent for most items tested. The predictive validity of the SERQ was superior to the RSI when it included the covariates of history of sinusitis, use of over-the-counter antacid medications, age, gender, and body mass index. CONCLUSIONS: The SERQ will serve as both a useful clinical and research tool by offering not only SER symptom information, like the RSI, but also information about the patient's medical history and medication usage that will facilitate use of the SERQ in research protocols. EBM rating: B-2b.
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U2 - 10.1016/j.otohns.2005.08.018
DO - 10.1016/j.otohns.2005.08.018
M3 - Article
C2 - 16399184
AN - SCOPUS:29944447481
SN - 0194-5998
VL - 134
SP - 73
EP - 80
JO - Otolaryngology - Head and Neck Surgery
JF - Otolaryngology - Head and Neck Surgery
IS - 1
ER -