Surfactant spreading and surface-compression-waves on thin liquid films

J. L. Bull, L. K. Nelson, J. T. Walsh, M. R. Glucksberg, S. Schurch, J. B. Grotberg

Research output: Contribution to journalArticle

Abstract

Surfactant spreading on a thin viscous film, in the presence of a pre-existing surfactant distribution, is investigated experimentally. The experiments are designed to provide a better understanding of the fundamental interfacial and fluid dynamics for spreading of an exogenous surfactant instilled into the lung. Quantitative measurements of spreading rates were conducted using a fluorescent exogenous surfactant (1-16:0-2-[12-[(7-nitro-2-1, 3-benzoxadiazol-4-yl)amino]dodecanoyl] phosphatidylcholine) that was excited by argon laser light as it spread on an air-glycerin interface in a petri dish. This interface was either clean or contained a level of non-fluorescent, pre-existing surfactant(palmitoyl-lauroyl-sn-glycero- 3-phosphocholine) which was varied. The surface behavior of these similar agents was shown to be nearly identical. It is found that pre-existing surfactant impedes surfactant spreading. However, fluorescent microspheres used as surface markers show that pre-existing surfactant facilitates the propagation of a compression-wave disturbance which travels faster than the leading edge of the new surfactant. The experimental results are compared to a mathematical model that accounts for the finite domain of the petri dish. The experimental results compare well with the theory.

Original languageEnglish (US)
JournalFASEB Journal
Volume11
Issue number3
StatePublished - Dec 1 1997

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Genetics

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    Bull, J. L., Nelson, L. K., Walsh, J. T., Glucksberg, M. R., Schurch, S., & Grotberg, J. B. (1997). Surfactant spreading and surface-compression-waves on thin liquid films. FASEB Journal, 11(3).