Abstract
Surgical resection, with the goal of maximal tumor removal, is now standard of care for the overwhelming majority of newly diagnosed gliomas. In order to achieve this goal while minimizing the risk of postoperative neurologic deficits, intraoperative brain mapping remains the gold standard. Recent advances in technical aspects of preoperative and intraoperative brain mapping, as well as our understanding of the functional anatomy of the human brain with respect to language, movement, sensation, and cognition, particularly at the subcortical level, have improved our ability to safely perform aggressive resective surgeries in eloquent areas. In this chapter, the functional anatomy of the human brain relevant to intrinsic tumor resection is reviewed. In addition, general principles governing surgical management of patients are highlighted, with a particular emphasis on awake brain mapping.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 31-47 |
| Number of pages | 17 |
| Journal | Cancer treatment and research |
| Volume | 163 |
| DOIs | |
| State | Published - Jan 1 2015 |
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Keywords
- Glioma surgery
- Mapping
ASJC Scopus subject areas
- Oncology
- Cancer Research
Cite this
}
Surgery for gliomas. / Tate, Matthew C.
In: Cancer treatment and research, Vol. 163, 01.01.2015, p. 31-47.Research output: Contribution to journal › Article
TY - JOUR
T1 - Surgery for gliomas
AU - Tate, Matthew C.
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Surgical resection, with the goal of maximal tumor removal, is now standard of care for the overwhelming majority of newly diagnosed gliomas. In order to achieve this goal while minimizing the risk of postoperative neurologic deficits, intraoperative brain mapping remains the gold standard. Recent advances in technical aspects of preoperative and intraoperative brain mapping, as well as our understanding of the functional anatomy of the human brain with respect to language, movement, sensation, and cognition, particularly at the subcortical level, have improved our ability to safely perform aggressive resective surgeries in eloquent areas. In this chapter, the functional anatomy of the human brain relevant to intrinsic tumor resection is reviewed. In addition, general principles governing surgical management of patients are highlighted, with a particular emphasis on awake brain mapping.
AB - Surgical resection, with the goal of maximal tumor removal, is now standard of care for the overwhelming majority of newly diagnosed gliomas. In order to achieve this goal while minimizing the risk of postoperative neurologic deficits, intraoperative brain mapping remains the gold standard. Recent advances in technical aspects of preoperative and intraoperative brain mapping, as well as our understanding of the functional anatomy of the human brain with respect to language, movement, sensation, and cognition, particularly at the subcortical level, have improved our ability to safely perform aggressive resective surgeries in eloquent areas. In this chapter, the functional anatomy of the human brain relevant to intrinsic tumor resection is reviewed. In addition, general principles governing surgical management of patients are highlighted, with a particular emphasis on awake brain mapping.
KW - Glioma surgery
KW - Mapping
UR - http://www.scopus.com/inward/record.url?scp=84916620260&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84916620260&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-12048-5_3
DO - 10.1007/978-3-319-12048-5_3
M3 - Article
C2 - 25468224
AN - SCOPUS:84916620260
VL - 163
SP - 31
EP - 47
JO - Cancer Treatment and Research
JF - Cancer Treatment and Research
SN - 0927-3042
ER -