Surgery of metabolic liver disease and disorders of biliary transport

Research output: Chapter in Book/Report/Conference proceedingChapter


Byler disease (a form of progressive familial intrahepatic cholestasis [PFIC]) is viewed by many as the prototype for genetic forms of biliary transport disorder. It was first described in the 1960s [3,4] as a cholestatic disease which affected members of the Amish community who were direct descendants of Jacob Byler and Nancy Kaufmann. This couple emigrated to Pennsylvania in the late eighteenth century and were originally from Switzerland.

Original languageEnglish (US)
Title of host publicationSurgery of the Liver, Bile Ducts and Pancreas in Children, Third Edition
PublisherCRC Press
Number of pages13
ISBN (Electronic)9781444181210
ISBN (Print)9781444181203
StatePublished - Jan 1 2017

ASJC Scopus subject areas

  • Medicine(all)


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