Surgical management of pyoderma gangrenosum: Case report and review

Murad Alam*, Marc E. Grossman, Paul Ira Schneiderman, Ralph S. Blume, Alan I. Benvenisty

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


BACKGROUND. Commonly used treatments for pyoderma gangrenosum are medical, with immunosuppressive agents employed most often. OBJECTIVE. To report a case and discuss the indications for radical surgical treatment of pyoderma gangrenosum. METHODS. Analysis of a case of Crohn's disease-associated pyoderma gangrenosum treated with immunosuppression followed by amputation, and a review of the literature on surgical management of pyoderma gangrenosum. RESULTS. In unstable patients with intractable multiple medical problems, surgical treatment of pyoderma gangrenosum may be indicated by the existence of these life-threatening comorbidities. The recent literature suggests that surgical management of pyoderma gangrenosum may also be appropriate in other special circumstances. CONCLUSIONS. Surgical management, including amputation, may have a role in the management of pyoderma gangrenosum. Further research is needed to delineate precisely the circumstances and patient factors that are appropriate indications for such surgery.

Original languageEnglish (US)
Pages (from-to)1063-1066
Number of pages4
JournalDermatologic Surgery
Issue number11
StatePublished - Nov 25 2000

ASJC Scopus subject areas

  • Surgery
  • Dermatology


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