Survey of ferroxidase expression and siderophore production in clinical isolates of Pseudomonas aeruginosa

Wilhelmina M. Huston, Adam J. Potter, Michael P. Jennings*, Jordi Rello, Alan R. Hauser, Alastair G. McEwan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Ferroxidase (encoded by the mco gene), a component of a ferrous iron uptake pathway in Pseudomonas aeruginosa, was detected in all of the 35 respiratory clinical isolates surveyed; in contrast, considerable variation in siderophore expression was observed. The ubiquitous expression of this periplasmic ferroxidase suggests that it plays a key role in iron uptake in this opportunistic pathogen.

Original languageEnglish (US)
Pages (from-to)2806-2809
Number of pages4
JournalJournal of clinical microbiology
Volume42
Issue number6
DOIs
StatePublished - Jun 2004

ASJC Scopus subject areas

  • Microbiology (medical)

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