Susceptibility of an inbred strain of guinea pigs to the induction of pancreatic adenocarcinoma by N methyl N nitrosourea

J. K. Reddy, D. J. Svoboda, M. S. Rao

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Adenocarcinoma of the pancreas developed by week 36 in 4 of 11 inbred strain 13 guinea pigs that survived weekly intragastric administration of 10 mg N methyl N nitrosourea/kg body weight for >6 months. The short induction period suggests that this inbred strain of guinea pigs is valuable in developing a suitable biologic model for pancreatic adenocarcinoma.

Original languageEnglish (US)
Pages (from-to)991-993
Number of pages3
JournalJournal of the National Cancer Institute
Volume52
Issue number3
DOIs
StatePublished - Jan 1 1974

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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