Susceptibility of an inbred strain of guinea pigs to the induction of pancreatic adenocarcinoma by N methyl N nitrosourea

J. K. Reddy; D. J. Svoboda; M. S. Rao

doi:10.1093/jnci/52.3.991

Susceptibility of an inbred strain of guinea pigs to the induction of pancreatic adenocarcinoma by N methyl N nitrosourea

J. K. Reddy, D. J. Svoboda, M. S. Rao

Pathology

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31 Scopus citations

Abstract

Adenocarcinoma of the pancreas developed by week 36 in 4 of 11 inbred strain 13 guinea pigs that survived weekly intragastric administration of 10 mg N methyl N nitrosourea/kg body weight for >6 months. The short induction period suggests that this inbred strain of guinea pigs is valuable in developing a suitable biologic model for pancreatic adenocarcinoma.

Original language	English (US)
Pages (from-to)	991-993
Number of pages	3
Journal	Journal of the National Cancer Institute
Volume	52
Issue number	3
DOIs	https://doi.org/10.1093/jnci/52.3.991
State	Published - 1974

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1093/jnci/52.3.991

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abstract = "Adenocarcinoma of the pancreas developed by week 36 in 4 of 11 inbred strain 13 guinea pigs that survived weekly intragastric administration of 10 mg N methyl N nitrosourea/kg body weight for >6 months. The short induction period suggests that this inbred strain of guinea pigs is valuable in developing a suitable biologic model for pancreatic adenocarcinoma.",

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Susceptibility of an inbred strain of guinea pigs to the induction of pancreatic adenocarcinoma by N methyl N nitrosourea

Abstract

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