Symptom Frequency and Distress from 5 to 10 Years After Heart Transplantation

Kathleen L Grady*, Edward Wang, Robert Higgins, Alain Heroux, Bruce Rybarczyk, James B. Young, Dave Pelegrin, Jennifer Czerr, Jon Kobashigawa, Julie Chait, David C. Naftel, Connie White Williams, Susan Myers, James K. Kirklin

*Corresponding author for this work

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background: Patterns of symptom frequency and distress have not been examined long-term after heart transplantation, nor have predictors of long-term symptom frequency and distress. This report identified the most commonly reported and distressful symptoms long-term after transplantation, described patterns of symptom frequency and distress over time, and examined predictors of symptom frequency and distress at 5 and 10 years after heart transplantation. Methods: The sample included 555 participants from a prospective, multisite, longitudinal study of quality of life outcomes. Patients were 78% male, 88% white, 79% married, and mean age of 54 years at time of heart transplantation. Data were collected using patient self-report and medical records review. Statistical analyses included descriptive statistics, Pearson correlations, t-tests, and generalized linear models. Results: Significant predictors of lower symptom frequency after heart transplantation were not having psychological problems and not having cardiac allograft vasculopathy at 5 years, and not having psychological problems and not having infection at 10 years. Significant predictors of less symptom distress were having more than a high school education, having no psychological problems, and having gout at 5 years, and being married at 10 years. Conclusions: Symptom frequency is low and symptom distress is moderate long-term after heart transplantation. Significant relationships exist between both demographic and clinical variables and symptom frequency and distress. Identification of the most common and bothersome symptoms after heart transplantation provides clinicians with important information from which to develop a plan of care.

Original languageEnglish (US)
Pages (from-to)759-768
Number of pages10
JournalJournal of Heart and Lung Transplantation
Volume28
Issue number8
DOIs
StatePublished - Aug 1 2009

Fingerprint

Heart Transplantation
Psychology
Gout
Self Report
Medical Records
Allografts
Longitudinal Studies
Linear Models
Transplantation
Quality of Life
Demography
Education
Infection

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

Cite this

Grady, Kathleen L ; Wang, Edward ; Higgins, Robert ; Heroux, Alain ; Rybarczyk, Bruce ; Young, James B. ; Pelegrin, Dave ; Czerr, Jennifer ; Kobashigawa, Jon ; Chait, Julie ; Naftel, David C. ; White Williams, Connie ; Myers, Susan ; Kirklin, James K. / Symptom Frequency and Distress from 5 to 10 Years After Heart Transplantation. In: Journal of Heart and Lung Transplantation. 2009 ; Vol. 28, No. 8. pp. 759-768.
@article{4da338d837cf4ba3a62b9abc7a4764aa,
title = "Symptom Frequency and Distress from 5 to 10 Years After Heart Transplantation",
abstract = "Background: Patterns of symptom frequency and distress have not been examined long-term after heart transplantation, nor have predictors of long-term symptom frequency and distress. This report identified the most commonly reported and distressful symptoms long-term after transplantation, described patterns of symptom frequency and distress over time, and examined predictors of symptom frequency and distress at 5 and 10 years after heart transplantation. Methods: The sample included 555 participants from a prospective, multisite, longitudinal study of quality of life outcomes. Patients were 78{\%} male, 88{\%} white, 79{\%} married, and mean age of 54 years at time of heart transplantation. Data were collected using patient self-report and medical records review. Statistical analyses included descriptive statistics, Pearson correlations, t-tests, and generalized linear models. Results: Significant predictors of lower symptom frequency after heart transplantation were not having psychological problems and not having cardiac allograft vasculopathy at 5 years, and not having psychological problems and not having infection at 10 years. Significant predictors of less symptom distress were having more than a high school education, having no psychological problems, and having gout at 5 years, and being married at 10 years. Conclusions: Symptom frequency is low and symptom distress is moderate long-term after heart transplantation. Significant relationships exist between both demographic and clinical variables and symptom frequency and distress. Identification of the most common and bothersome symptoms after heart transplantation provides clinicians with important information from which to develop a plan of care.",
author = "Grady, {Kathleen L} and Edward Wang and Robert Higgins and Alain Heroux and Bruce Rybarczyk and Young, {James B.} and Dave Pelegrin and Jennifer Czerr and Jon Kobashigawa and Julie Chait and Naftel, {David C.} and {White Williams}, Connie and Susan Myers and Kirklin, {James K.}",
year = "2009",
month = "8",
day = "1",
doi = "10.1016/j.healun.2009.04.020",
language = "English (US)",
volume = "28",
pages = "759--768",
journal = "Journal of Heart and Lung Transplantation",
issn = "1053-2498",
publisher = "Elsevier USA",
number = "8",

}

Grady, KL, Wang, E, Higgins, R, Heroux, A, Rybarczyk, B, Young, JB, Pelegrin, D, Czerr, J, Kobashigawa, J, Chait, J, Naftel, DC, White Williams, C, Myers, S & Kirklin, JK 2009, 'Symptom Frequency and Distress from 5 to 10 Years After Heart Transplantation', Journal of Heart and Lung Transplantation, vol. 28, no. 8, pp. 759-768. https://doi.org/10.1016/j.healun.2009.04.020

Symptom Frequency and Distress from 5 to 10 Years After Heart Transplantation. / Grady, Kathleen L; Wang, Edward; Higgins, Robert; Heroux, Alain; Rybarczyk, Bruce; Young, James B.; Pelegrin, Dave; Czerr, Jennifer; Kobashigawa, Jon; Chait, Julie; Naftel, David C.; White Williams, Connie; Myers, Susan; Kirklin, James K.

In: Journal of Heart and Lung Transplantation, Vol. 28, No. 8, 01.08.2009, p. 759-768.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Symptom Frequency and Distress from 5 to 10 Years After Heart Transplantation

AU - Grady, Kathleen L

AU - Wang, Edward

AU - Higgins, Robert

AU - Heroux, Alain

AU - Rybarczyk, Bruce

AU - Young, James B.

AU - Pelegrin, Dave

AU - Czerr, Jennifer

AU - Kobashigawa, Jon

AU - Chait, Julie

AU - Naftel, David C.

AU - White Williams, Connie

AU - Myers, Susan

AU - Kirklin, James K.

PY - 2009/8/1

Y1 - 2009/8/1

N2 - Background: Patterns of symptom frequency and distress have not been examined long-term after heart transplantation, nor have predictors of long-term symptom frequency and distress. This report identified the most commonly reported and distressful symptoms long-term after transplantation, described patterns of symptom frequency and distress over time, and examined predictors of symptom frequency and distress at 5 and 10 years after heart transplantation. Methods: The sample included 555 participants from a prospective, multisite, longitudinal study of quality of life outcomes. Patients were 78% male, 88% white, 79% married, and mean age of 54 years at time of heart transplantation. Data were collected using patient self-report and medical records review. Statistical analyses included descriptive statistics, Pearson correlations, t-tests, and generalized linear models. Results: Significant predictors of lower symptom frequency after heart transplantation were not having psychological problems and not having cardiac allograft vasculopathy at 5 years, and not having psychological problems and not having infection at 10 years. Significant predictors of less symptom distress were having more than a high school education, having no psychological problems, and having gout at 5 years, and being married at 10 years. Conclusions: Symptom frequency is low and symptom distress is moderate long-term after heart transplantation. Significant relationships exist between both demographic and clinical variables and symptom frequency and distress. Identification of the most common and bothersome symptoms after heart transplantation provides clinicians with important information from which to develop a plan of care.

AB - Background: Patterns of symptom frequency and distress have not been examined long-term after heart transplantation, nor have predictors of long-term symptom frequency and distress. This report identified the most commonly reported and distressful symptoms long-term after transplantation, described patterns of symptom frequency and distress over time, and examined predictors of symptom frequency and distress at 5 and 10 years after heart transplantation. Methods: The sample included 555 participants from a prospective, multisite, longitudinal study of quality of life outcomes. Patients were 78% male, 88% white, 79% married, and mean age of 54 years at time of heart transplantation. Data were collected using patient self-report and medical records review. Statistical analyses included descriptive statistics, Pearson correlations, t-tests, and generalized linear models. Results: Significant predictors of lower symptom frequency after heart transplantation were not having psychological problems and not having cardiac allograft vasculopathy at 5 years, and not having psychological problems and not having infection at 10 years. Significant predictors of less symptom distress were having more than a high school education, having no psychological problems, and having gout at 5 years, and being married at 10 years. Conclusions: Symptom frequency is low and symptom distress is moderate long-term after heart transplantation. Significant relationships exist between both demographic and clinical variables and symptom frequency and distress. Identification of the most common and bothersome symptoms after heart transplantation provides clinicians with important information from which to develop a plan of care.

UR - http://www.scopus.com/inward/record.url?scp=67650735193&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67650735193&partnerID=8YFLogxK

U2 - 10.1016/j.healun.2009.04.020

DO - 10.1016/j.healun.2009.04.020

M3 - Article

C2 - 19632570

AN - SCOPUS:67650735193

VL - 28

SP - 759

EP - 768

JO - Journal of Heart and Lung Transplantation

JF - Journal of Heart and Lung Transplantation

SN - 1053-2498

IS - 8

ER -