Symptoms of depression and anxiety in patients with thalassemia: Prevalence and correlates in the thalassemia longitudinal cohort

Lauren Mednick*, Shuli Yu, Felicia Trachtenberg, Yan Xu, Dorothy A. Kleinert, Patricia J. Giardina, Janet L. Kwiatkowski, Dru Foote, Vivekanandan Thayalasuthan, John B. Porter, Alexis A. Thompson, Leann Schilling, Charles T. Quinn, Ellis J. Neufeld, Robert Yamashita

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Thalassemia is an inherited blood disorder that requires lifelong adherence to a complicated and burdensome medical regimen which could potentially impact emotional functioning of patients. The importance of understanding and promoting healthy emotional functioning is crucial not only to psychological well-being, but also to physical health as it has been shown to impact adherence to medical regimens [1-4]. The current study aimed to [1] determine the prevalence of depressive and anxiety symptoms in adolescent and adult patients with thalassemia; and [2] explore possible demographic, medical, and psychosocial correlates of these symptoms in 276 patients (14-58 years old, M age = 27.83; 52% female). Overall, most patients did not report experiencing significant symptoms of anxiety and depression (33% of participants indicated experiencing symptoms of anxiety and 11% symptoms of depression). Females and older patients were more likely to experience these symptoms than males and younger patients. Symptoms of anxiety and depression were positively associated with self-report of difficulty with adherence and negatively associated with quality of life. Given these findings, regular screening for anxiety and depression symptoms could help to identify at-risk individuals to provide them with appropriate psychological support with the goal of improving both emotional and physical health.

Original languageEnglish (US)
Pages (from-to)802-805
Number of pages4
JournalAmerican Journal of Hematology
Volume85
Issue number10
DOIs
StatePublished - Oct 2010

ASJC Scopus subject areas

  • Hematology

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