Syndromic Surveillance Using Ambulatory Electronic Health Records

George Hripcsak*, Nicholas D. Soulakis, Li Li, Frances P. Morrison, Albert M. Lai, Carol Friedman, Neil S. Calman, Farzad Mostashari

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

45 Scopus citations


Objective: To assess the performance of electronic health record data for syndromic surveillance and to assess the feasibility of broadly distributed surveillance. Design: Two systems were developed to identify influenza-like illness and gastrointestinal infectious disease in ambulatory electronic health record data from a network of community health centers. The first system used queries on structured data and was designed for this specific electronic health record. The second used natural language processing of narrative data, but its queries were developed independently from this health record. Both were compared to influenza isolates and to a verified emergency department chief complaint surveillance system. Measurements: Lagged cross-correlation and graphs of the three time series. Results: For influenza-like illness, both the structured and narrative data correlated well with the influenza isolates and with the emergency department data, achieving cross-correlations of 0.89 (structured) and 0.84 (narrative) for isolates and 0.93 and 0.89 for emergency department data, and having similar peaks during influenza season. For gastrointestinal infectious disease, the structured data correlated fairly well with the emergency department data (0.81) with a similar peak, but the narrative data correlated less well (0.47). Conclusions: It is feasible to use electronic health records for syndromic surveillance. The structured data performed best but required knowledge engineering to match the health record data to the queries. The narrative data illustrated the potential performance of a broadly disseminated system and achieved mixed results.

Original languageEnglish (US)
Pages (from-to)354-361
Number of pages8
JournalJournal of the American Medical Informatics Association
Issue number3
StatePublished - May 2009

ASJC Scopus subject areas

  • Health Informatics


Dive into the research topics of 'Syndromic Surveillance Using Ambulatory Electronic Health Records'. Together they form a unique fingerprint.

Cite this