Synthesis and conformational behaviour of tetra-anthranilides

Alireza Hoorfar*, W. David Ollis, J. Fraser Stoddart, David J. Williams

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The tetra-anthranilide derivatives (5)-(7) have been synthesised. X-Ray crystallography shows that N,N′,N″-trimethyltetra-anthranilide (5) adopts a conformation with three trans - and one cis-amide linkages in the solid state. Dynamic 1H n.m.r. spectroscopy indicates that N-benzyl-N′,N″,N′″-trimethyltetra-anthranilide (7) exists as an interconverting ternary mixture of chiral non-planar conformational diastereoisomers in solution.

Original languageEnglish (US)
Pages (from-to)4211-4214
Number of pages4
JournalTetrahedron Letters
Issue number43
StatePublished - 1980

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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