Synthesis and evaluation of MR probes for targeted-reporter imaging

Kirti Dhingra Verma, Justin O. Massing, Sarah G. Kamper, Christiane E. Carney, Keith W. Macrenaris, James P. Basilion*, Thomas J. Meade

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Visualizing disease heterogeneity remains a challenging task since most imaging agents are targeted to a single receptor. We describe the development of an MR platform able to report on multiple molecular events. Enzyme activation and enhanced cellular uptake of this modular probe make it suitable for subsequent targeted-reporter imaging applications.

Original languageEnglish (US)
Pages (from-to)5764-5768
Number of pages5
JournalChemical Science
Volume8
Issue number8
DOIs
StatePublished - 2017

ASJC Scopus subject areas

  • Chemistry(all)

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