Synthesis and structure of a trinuclear chromium(III)-nicotinic acid complex

Enrique Gonzalez-Vergara; Jack Hegenauer; Paul Saltman; Michal Sabat; James A. Ibers

doi:10.1016/S0020-1693(00)85799-0

Synthesis and structure of a trinuclear chromium(III)-nicotinic acid complex

Enrique Gonzalez-Vergara^*, Jack Hegenauer, Paul Saltman, Michal Sabat, James A. Ibers

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

The reaction of nicotinic acid (nic), chromic perchlorate hexahydrate, and sodium perchlorate in aqueous solution affords a Cr(III)-vitamin complex whose composition has been established to be Na[Cr₃O(nicH)₆(H₂O)₃][ClO₄]₈·nicH·6H₂O, based on analytical data and a single-crystal X-ray analysis. In the [Cr₃O(nicH)₆(H₂O)₃]⁺⁷ ion a central oxygen atom is bonded to three chromium atoms. The nicotinic and zwitterions bridge these chromium centers through the carboxylate oxygen atoms. On each chromium atom a water oxygen, trans to the central oxygen atom, complexes the octahedral coordination. The ion has crystallographically imposed symmetry 6. The binding of nicotinic acid in this Cr(III)-nicotinic acid complex is significantly different from that currently proposed for the glucose tolerance factor.

Original language	English (US)
Pages (from-to)	115-118
Number of pages	4
Journal	Inorganica Chimica Acta
Volume	66
Issue number	C
DOIs	https://doi.org/10.1016/S0020-1693(00)85799-0
State	Published - 1982

Funding

We thank the National Council of Science and Technology (CONACYT-Mexico) for fellowship support of E.G.-V. This work was supported at the University of California by USPHS Grant AM 12386 from the National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseasesa nd at Northwestern University by Grant HL 131 57 of the National Institutes of Health.

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Inorganic Chemistry
Materials Chemistry

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title = "Synthesis and structure of a trinuclear chromium(III)-nicotinic acid complex",

abstract = "The reaction of nicotinic acid (nic), chromic perchlorate hexahydrate, and sodium perchlorate in aqueous solution affords a Cr(III)-vitamin complex whose composition has been established to be Na[Cr3O(nicH)6(H2O)3][ClO4]8·nicH·6H2O, based on analytical data and a single-crystal X-ray analysis. In the [Cr3O(nicH)6(H2O)3]+7 ion a central oxygen atom is bonded to three chromium atoms. The nicotinic and zwitterions bridge these chromium centers through the carboxylate oxygen atoms. On each chromium atom a water oxygen, trans to the central oxygen atom, complexes the octahedral coordination. The ion has crystallographically imposed symmetry 6. The binding of nicotinic acid in this Cr(III)-nicotinic acid complex is significantly different from that currently proposed for the glucose tolerance factor.",

author = "Enrique Gonzalez-Vergara and Jack Hegenauer and Paul Saltman and Michal Sabat and Ibers, {James A.}",

note = "Funding Information: We thank the National Council of Science and Technology (CONACYT-Mexico) for fellowship support of E.G.-V. This work was supported at the University of California by USPHS Grant AM 12386 from the National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseasesa nd at Northwestern University by Grant HL 131 57 of the National Institutes of Health.",

year = "1982",

doi = "10.1016/S0020-1693(00)85799-0",

language = "English (US)",

volume = "66",

pages = "115--118",

journal = "Inorganica Chimica Acta",

issn = "0020-1693",

publisher = "Elsevier B.V.",

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TY - JOUR

T1 - Synthesis and structure of a trinuclear chromium(III)-nicotinic acid complex

AU - Gonzalez-Vergara, Enrique

AU - Hegenauer, Jack

AU - Saltman, Paul

AU - Sabat, Michal

AU - Ibers, James A.

N1 - Funding Information: We thank the National Council of Science and Technology (CONACYT-Mexico) for fellowship support of E.G.-V. This work was supported at the University of California by USPHS Grant AM 12386 from the National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseasesa nd at Northwestern University by Grant HL 131 57 of the National Institutes of Health.

PY - 1982

Y1 - 1982

N2 - The reaction of nicotinic acid (nic), chromic perchlorate hexahydrate, and sodium perchlorate in aqueous solution affords a Cr(III)-vitamin complex whose composition has been established to be Na[Cr3O(nicH)6(H2O)3][ClO4]8·nicH·6H2O, based on analytical data and a single-crystal X-ray analysis. In the [Cr3O(nicH)6(H2O)3]+7 ion a central oxygen atom is bonded to three chromium atoms. The nicotinic and zwitterions bridge these chromium centers through the carboxylate oxygen atoms. On each chromium atom a water oxygen, trans to the central oxygen atom, complexes the octahedral coordination. The ion has crystallographically imposed symmetry 6. The binding of nicotinic acid in this Cr(III)-nicotinic acid complex is significantly different from that currently proposed for the glucose tolerance factor.

AB - The reaction of nicotinic acid (nic), chromic perchlorate hexahydrate, and sodium perchlorate in aqueous solution affords a Cr(III)-vitamin complex whose composition has been established to be Na[Cr3O(nicH)6(H2O)3][ClO4]8·nicH·6H2O, based on analytical data and a single-crystal X-ray analysis. In the [Cr3O(nicH)6(H2O)3]+7 ion a central oxygen atom is bonded to three chromium atoms. The nicotinic and zwitterions bridge these chromium centers through the carboxylate oxygen atoms. On each chromium atom a water oxygen, trans to the central oxygen atom, complexes the octahedral coordination. The ion has crystallographically imposed symmetry 6. The binding of nicotinic acid in this Cr(III)-nicotinic acid complex is significantly different from that currently proposed for the glucose tolerance factor.

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VL - 66

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JO - Inorganica Chimica Acta

JF - Inorganica Chimica Acta

IS - C

ER -

Synthesis and structure of a trinuclear chromium(III)-nicotinic acid complex

Abstract

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ASJC Scopus subject areas

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