Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide

Keyphrases

• Cellular Targets 100%
• Neopeltolide 100%
• Mammalian Cells 66%
• Antiproliferative Activity 66%
• Genetic Analysis 33%
• Growth Inhibition 33%
• Mechanism of Action 33%
• Energy Metabolism 33%
• Mitochondrial Electron Transport Chain 33%
• Biochemical Tools 33%
• Cellular Growth 33%
• Electron Transport Chain Complexes 33%
• Natural Products 33%
• Yeast Cells 33%
• Biochemical Assessment 33%
• Drug Sensitivity 33%
• Glycerol 33%
• Marine Natural Products 33%
• Galactose 33%
• Mitochondrial ATP Production 33%
• Cytochrome bc1 Complex 33%
• Pharmacological Evaluation 33%
• Marine Macrolides 33%

Chemistry

• Mammalian Cell 100%
• Antiproliferative 100%
• Marine Natural Products 50%
• Macrolide Antibiotic Agent 50%
• Growth Inhibition 50%
• ATP 50%
• Cytochrome 50%
• Electron Transport 50%
• Natural Product 50%
• Galactose 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Natural Product 100%
• Macrolide 50%
• Antiproliferative Activity 50%
• Coenzyme Q - Cytochrome C Reductase 50%
• Galactose 50%
• Adenosine Triphosphate 50%