Synthesis of 2-substituted-3-phytyl-1,4-naphthoquinone epoxides

Robert P. Ryall, Richard B Silverman

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Hydroxymethylation of 2-phytyl-l,4-naphthohydroquinone fol- lowed by epoxidation gives 2-hydroxymethyl-3-phytyl-l,4-naphthoquinone epoxide, which is converted to the corresponding 2-fluoromethyl-, 2-chloromethyl-, and 2-difluoromethyl- analogues. The latter compound is prepared from the 2-formyl analogue.

Original languageEnglish (US)
Pages (from-to)431-438
Number of pages8
JournalSynthetic Communications
Issue number3
StatePublished - Jan 1 1990

ASJC Scopus subject areas

  • Organic Chemistry

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