Synthesis of infective poliovirus in BSC-1 monkey cells enucleated with cytochalasin B

Robert Pollack*, Robert Goldman

*Corresponding author for this work

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

BSC-1 monkey kidney cells were enucleated by two cycles of centrifugation in the presence of cytochalasin B. The resulting populations contained 99.5 percent enucleated cells. After infection, newly synthesized poliovirus was recovered from the enucleated populations. Final virus yield per enucleated cell was about one-fifth the yield per infected untreated cell.

Original languageEnglish (US)
Pages (from-to)915-916
Number of pages2
JournalScience
Volume179
Issue number4076
DOIs
StatePublished - Jan 1 1973

ASJC Scopus subject areas

  • General

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