Synthesis of iron oxide nanocube patched Janus magnetic nanocarriers for cancer therapeutic applications

Wentao Zhang, Hyunjun Choi, Bo Yu, Dong Hyun Kim*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Janus magnetic particles, which can be customized for various multifunctionalities, have promising potential for cancer therapeutic carriers. Herein we synthesized iron oxide nanocube (IONC) patched Janus magnetic nanocarriers (IONCs-P-JMNC) using emulsification and interface evaporation/assembly. Novel IONC patches were generated with an optimal ratio of CTAB and oleic acid coated IONCs in the emulsion. 2D assembled IONC patched Janus magnetic porous silica nanocarriers (IONCs-P-JMNC) formed with the addition of tetraethyl orthosilicate (TEOS). The anisotropically IONC patched Janus nanocarriers, allowing effective MRI T2∗ contrast and magneto-mechanical properties, are expected to be used for a new type of multifunctional carrier in cancer therapeutic applications. This journal is

Original languageEnglish (US)
Pages (from-to)8810-8813
Number of pages4
JournalChemical Communications
Volume56
Issue number62
DOIs
StatePublished - Aug 11 2020

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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