Synthesis of multimeric MR contrast agents for cellular imaging

Ying Song, Ellen K. Kohlmeir, Thomas J. Meade

Research output: Contribution to journalArticlepeer-review

156 Scopus citations

Abstract

We have prepared a series of molecular multimeric MR contrast agents for cell labeling that are easy to synthesize, relatively low molecular weight, and biocompatible. The relaxivities of the agents range from 17 to 85 mM-1s-1. Cellular uptake is concentration dependent and viability is excellent. MR images of cell pellets reveal a marked increase in observed signal intensity.

Original languageEnglish (US)
Pages (from-to)6662-6663
Number of pages2
JournalJournal of the American Chemical Society
Volume130
Issue number21
DOIs
StatePublished - May 28 2008

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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