TY - JOUR
T1 - Synthesis of N-substituted indole-3-carboxylic acid derivatives via Cu(I)-catalyzed intramolecular amination of aryl bromides
AU - Melkonyan, Ferdinand S.
AU - Karchava, Alexander V.
AU - Yurovskaya, Marina A.
PY - 2008/6/6
Y1 - 2008/6/6
N2 - (Chemical Equation Presented) A variety of N-alkylated and N-arylated derivatives of methyl 1H-indole-3-carboxylate were synthesized efficiently via Ullmann-type intramolecular arylamination, using the CuI-K3PO 4-DMF system. This catalytic amination procedure can be performed with good to high yields under mild conditions under an air atmosphere.
AB - (Chemical Equation Presented) A variety of N-alkylated and N-arylated derivatives of methyl 1H-indole-3-carboxylate were synthesized efficiently via Ullmann-type intramolecular arylamination, using the CuI-K3PO 4-DMF system. This catalytic amination procedure can be performed with good to high yields under mild conditions under an air atmosphere.
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U2 - 10.1021/jo800630v
DO - 10.1021/jo800630v
M3 - Article
C2 - 18471015
AN - SCOPUS:44949150209
SN - 0022-3263
VL - 73
SP - 4275
EP - 4278
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
IS - 11
ER -