The synthesis and characterization of three new five-atom-linked “capped” porphyrins, 6, 12, and 18, are reported. The general synthetic procedure involves synthesis of a tetraaldehyde “cap” by reacting the five-atom “arm” with 1,2,4,5-tetrahydroxybenzene in DMSO solvent in the presence of KOH. The tetraaldehyde and pyrrole are reacted to form the capped porphyrin. These compounds are useful as models for the active sites of heme proteins.
ASJC Scopus subject areas
- Organic Chemistry