Systematic symptom management in the IMPACT Consortium: rationale and design for 3 effectiveness-implementation trials

Ashley Wilder Smith*, Lisa Dimartino, Sofia F. Garcia, Sandra A. Mitchell, Kathryn J. Ruddy, Justin D. Smith, Sandra L. Wong, September Cahue, David Cella, Roxanne E. Jensen, Michael J. Hassett, Christine Hodgdon, Barbara Kroner, Raymond U. Osarogiagbon, Jennifer Popovic, Kimberly Richardson, Deborah Schrag, Andrea L. Cheville

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Cancer and its treatment produce deleterious symptoms across the phases of care. Poorly controlled symptoms negatively affect quality of life and result in increased health-care needs and hospitalization. The Improving the Management of symPtoms during And following Cancer Treatment (IMPACT) Consortium was created to develop 3 large-scale, systematic symptom management systems, deployed through electronic health record platforms, and to test them in pragmatic, randomized, hybrid effectiveness and implementation trials. Here, we describe the IMPACT Consortium's conceptual framework, its organizational components, and plans for evaluation. The study designs and lessons learned are highlighted in the context of disruptions related to the COVID-19 pandemic.

Original languageEnglish (US)
Article numberpkad073
JournalJNCI Cancer Spectrum
Volume7
Issue number6
DOIs
StatePublished - Dec 1 2023

Funding

The IMPACT Consortium is a Cancer Moonshot Research Initiative under the authorization of the 2016 United States 21st Century Cures Act. Research reported in this publication was supported by the NCI of the National Institutes of Health under award No. UM1CA233033 (Mayo Clinic, Rochester, MN), UM1CA233035 (Northwestern University, Chicago, IL), UM1CA233080 (Baptist Health System, Memphis, TN; Dana-Farber Cancer Institute, Boston, MA; Dartmouth-Hitchcock Medical Center, Lebanon, NH; Lifespan Health System, Providence, RI; Maine Medical Center, Portland, ME; and West Virginia University, Morgantown, WV), and U24CA232980 (RTI International, Research Triangle Park, NC).

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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